Guidance

Hepatitis B: vaccine recommendations during supply constraints

Vaccine recommendations for adults and children during periods of vaccine supply constraints.

Documents

Plan for phased re-introduction of hepatitis B vaccine for lower priority groups 2018

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Hepatitis B: vaccine recommendations during supply constraints

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Temporary Addendum: Combined hepatitis A and B vaccine use in travellers

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What to do if you have to wait for a dose of hepatitis B vaccine: advice for patients

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Details

Hepatitis B vaccine supplies

GSK are confident that planned supplies of adult and paediatric vaccine (Engerix B®) and renal vaccine (Fendrix®) are now sufficient to supply the UK market. Combined hepatitis A and B vaccine vaccines (Twinrix® and Ambirix®) are also available.

MSD UK expects current supplies of adult vaccine (HBvaxPRO™ 10mcgs) to last until October 2018 and supplies will not resume until 2020. Supplies of HBvaxPRO™ 5mcgs and limited supplies of HBvaxPRO™ 40mcgs remain available via AAH, the MSD nominated wholesaler, and are recommended for use in individuals prioritised by PHE.

PHE and DHSC have agreed to accelerate the phased re-introduction of vaccine outlined in the recovery plan, so that vaccine is now available for all priority groups 1 to 4.

This means that:

a) vaccine can be ordered for all health and social care clinical and non-clinical staff and healthcare students who are at risk of blood and body fluid exposure, including for groups where vaccine ordering was due to open in late summer to early autumn.

b) vaccine is also now available for travel. Visit the NaTHNaC website for indications for hepatitis B vaccination prior to travel.

To prevent excessive stockpiling and to ensure backlog or catch up vaccination can continue, some ordering restrictions will remain in place. If a vaccine order cannot be fulfilled by one manufacturer, please check with another.

As forecasts are dependent on expected deliveries and sales, we will continue to monitor the situation and update as required

Plan for phased re-introduction of hepatitis B vaccine for lower priority groups 2018.

Improved supplies of hepatitis B vaccine are expected in 2018. This provides an update on the phased reintroduction of monovalent hepatitis B vaccine and advice on accessing vaccine for more patient and health and social care staff groups.

Hepatitis B: vaccine recommendations during supply constraints

Hepatitis B immunisation recommendations have been developed in light of the recent global shortages of hepatitis B vaccine affecting the UK supply.

These recommendations include advice on prioritisation and dose sparing to preserve adult and paediatric monovalent hepatitis B vaccine stock for those at highest immediate need.

Temporary addendum on use of combined hepatitis A and B vaccine in travellers

This provides further advice on prioritisation of travellers now that supply of combined hepatitis A and B vaccine has improved.

What to do if you have to wait for a dose of hepatitis B vaccine: advice for patients

This factsheet has been produced for healthcare workers to download and give to patients who have to wait to have hepatitis B vaccination due to vaccine shortages.

Published 21 July 2017
Last updated 12 July 2018 + show all updates
  1. GSK is confident that planned supplies of adult and paediatric vaccine (Engerix B®) and renal vaccine (Fendrix®) are now sufficient to supply the UK market. PHE and DHSC have agreed to accelerate the phased reintroduction of vaccine outlined in the recovery plan, so that vaccine is now available for all priority groups 1 to 4.
  2. Improved supplies of hepatitis B vaccine are expected in 2018. This guidance provides an update and advice on accessing vaccine for more patient groups.
  3. Added further advice on using combined hepatitis A and B vaccine in travellers.
  4. Revised guidance on vaccine during periods of vaccine supply constraints.
  5. Added: factsheet for healthcare workers to give to patients who have to wait for a dose of hepatitis B vaccine.
  6. Factsheet removed.
  7. Added factsheet for healthcare workers to give to patients who cannot have hepatitis B vaccination due to vaccine shortages.
  8. Updated guidance as of 4 August 2017.
  9. First published.