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116 updates

About Obstetrics, gynaecology and fertility

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116 updates

About Obstetrics, gynaecology and fertility

Oral retinoids: pregnancy prevention—reminder of measures to minimise teratogenic risk

The risk of foetal malformation with oral retinoids is extremely high, even when used at a low dose or for a short time during pregnancy. All oral retinoids have an associated Pregnancy Prevention Programme (PPP), which is s…
- Therapeutic area: Dermatology and 2 others
- Published: 11 December 2014
Cyproterone acetate with ethinylestradiol (co-cyprindiol): balance of benefits and risks remains positive

Updated prescribing advice provided.
- Therapeutic area: Dermatology and 2 others
- Published: 11 December 2014
Antipsychotics: risk of extrapyramidal effects or withdrawal symptoms in newborns

Risk of extrapyramidal effects or withdrawal symptoms (or both) in newborns after maternal use of antipsychotics during the third trimester of pregnancy.
- Therapeutic area: Obstetrics, gynaecology and fertility and 1 others
- Published: 11 December 2014
Yasmin: risk of venous thromboembolism higher than levonorgestrel-containing pills

Risk of venous thromboembolism (VTE) for drospirenone-containing combined oral contraceptives (COCs), including Yasmin, is higher than for levonorgestrel-containing COCs.
- Therapeutic area: Obstetrics, gynaecology and fertility
- Published: 11 December 2014
Bisphosphonates: atypical femoral fractures

Atypical femoral fractures reported rarely with bisphosphonate therapy, mainly in patients receiving long-term treatment for osteoporosis.
- Therapeutic area: Cancer and 3 others
- Published: 11 December 2014
Implanon contraceptive implant: information for women and healthcare professionals
- Therapeutic area: Obstetrics, gynaecology and fertility
- Published: 11 December 2014
Oral bisphosphonates: oesophageal cancer risk—insufficient evidence of a link

Insufficient evidence to confirm a link between oral bisphosphonate use and an increased risk of oesophageal cancer.
- Therapeutic area: Cancer and 2 others
- Published: 11 December 2014
Implanon contraceptive implant: changing to Nexplanon

All healthcare professionals trained in inserting Implanon must make sure they are trained in using Nexplanon before the changeover.
- Therapeutic area: Obstetrics, gynaecology and fertility
- Published: 11 December 2014
Bisphosphonates: osteonecrosis of the jaw

All patients with cancer should have a dental check-up before bisphosphonate treatment.
- Therapeutic area: Cancer and 4 others
- Published: 11 December 2014
Bisphosphonates: atrial fibrillation

Clinical trial results suggest an increased risk of atrial fibrillation for zoledronic acid (Aclasta▼), pamidronic acid, and possibly for alendronic acid, although the balance-risk remains favourable for bisphosphonates.
- Therapeutic area: Cancer and 3 others
- Published: 11 December 2014
Hormonal contraceptives: cervical cancer

Latest evidence suggests long-term use of combined oral contraceptives or progestogen-only injectable contraceptives is associated with a small increased risk of cervical cancer.
- Therapeutic area: Obstetrics, gynaecology and fertility
- Published: 11 December 2014
Combined oral contraceptives show they can prevent ovarian cancer

New study shows use of oral contraceptives reduces risk of ovarian cancer.
- Therapeutic area: Obstetrics, gynaecology and fertility
- Published: 11 December 2014
Codeine: very rare risk of side-effects in breastfed babies

Breastfed babies might very rarely develop side-effects due to the presence of morphine in breast milk.
- Therapeutic area: Obstetrics, gynaecology and fertility and 2 others
- Published: 11 December 2014
Ecoflac infusion solutions: risk of air embolism

To avoid the risk of air embolism, these products should not be infused under pressure.
- Therapeutic area: Anaesthesia and intensive care and 22 others
- Published: 11 December 2014
Tibolone: benefit-risk balance

Increased risk of stroke in older women should be taken into account in prescribing decisions.
- Therapeutic area: Endocrinology, diabetology and metabolism and 1 others
- Published: 11 December 2014
Hormone-replacement therapy: updated advice

Before prescribing hormone-replacement therapy, healthcare professionals should consider carefully the potential benefits and risks for every woman
- Therapeutic area: Endocrinology, diabetology and metabolism and 1 others
- Published: 11 December 2014

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