Combined hormonal contraceptives: risk of venous thromboembolism
- Medicines and Healthcare products Regulatory Agency
- 12 March 2014
- Therapeutic area:
- Obstetrics, gynaecology and fertility
Non-hormonal or progestogen-only contraception should be considered in some situations.
Article date: March 2014
The February 2014 edition of Drug Safety Update included an article about combined hormonal contraceptives (CHCs) and risk of venous thromboembolism. This article refers to a letter that was sent to healthcare professionals through the Central Alerting System on Jan 22, 2014. Annexes 2–4 of the letter advise what contraception a woman should use instead of CHCs in the event of: major surgery; a period of prolonged immobilisation; or if she smokes and is older than 35 years.
The annexes recommend that a non-hormonal form of contraception should be used in these situations; however, they ought to have stated that a different form of contraception should be used. This clarified advice allows for use of progestogen-only contraception or non-hormonal contraception. Correct information is provided on the MHRA website.
Published: 12 March 2014
Therapeutic area: Obstetrics, gynaecology and fertility