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Medicines, medical devices

Guidance and regulation

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  • Consumer advice and details of how to report problems with e-cigarettes with guidance on how to place an e-cigarette on the market in Great Britain and Northern Ireland, including the notification scheme.

  • How the MHRA processes variations to marketing authorisations.

  • Information about medical devices that the public can buy for personal use and how we make sure they are safe and effective.

  • Guide for marketing authorisation holders, including qualified person responsible for pharmacovigilance (PV) and pharmacovigilance system master files (PSMF).

  • Information on the alignment of the amended UK clinical trial legislation with the Declaration of Helsinki, prioritising UK law where conflicts arise.

  • This document provides guidance on the data integrity expectations that should be considered by organisations involved in any aspect of the pharmaceutical lifecycle or GLP studies regulated by MHRA.

  • Guidance for UK wholesalers and manufacturers on how to import human medicines including unlicensed medicines, how to apply for a licence and how much it costs.

  • How the MHRA makes decisions on whether a borderline product is a medical device and which risk class should apply.

  • How to apply for a traditional herbal registration (THR) to market a herbal medicine in the UK.

  • How we regulate in vitro diagnostic medical devices (IVDs) that are placed on the UK market.

  • The Medicines and Healthcare Regulatory Agency have launched RegulatoryConnect, a service that provides the capability to track applications and view live authorisation details.

  • Keep up to date with the latest information from the UK GLP monitoring authority.

  • Information about the MHRA graduate scheme which is currently closed for applications.

  • The MHRA will review applications for orphan designation at the time of a marketing authorisation (MA) or variation application.

  • The eMIT provides information about prices and usage for generic drugs and pharmaceutical products.

  • Guidance on out of specification investigations, including definitions and laboratory analysis and phase I,II and III investigations.

  • This guidance clarifies the expectations on the application of the EU guidance on good pharmacovigilance practices (GVP)

  • Information about Clinical Trials Regulations outlining expanded enforcement provisions, offences, and compliance requirements for sponsors and investigators.

  • Information about how the MHRA regulates medical devices in Northern Ireland and what legislation applies to manufacturers and suppliers.

  • You must get permission to export certain drugs and medicines.