Guidance

Clostridioides difficile infection: guidance on management and treatment

Options, agents, recommendations and algorithms for the treatment of Clostridioides difficile (C. difficile) infection.

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This guidance is out of date and has been replaced by Clostridioides difficile infection: guidance on management and treatment.

Documents

Updated guidance on the management and treatment of C. difficile infection

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Details

The antimicrobial treatment recommendations in the existing Public Health England (PHE) Clostridioides difficile: guidance on management and treatment (2013) have been superseded by the National Institute for Health and Care Excellence (NICE) guideline on Clostridioides difficile infection (CDI).

A full update to the current PHE CDI guidelines is planned for later this year. Please continue to refer to the current PHE guidance for:

  • management of life-threatening disease
  • guidance on diagnosis
  • guidance on infection control
Published 1 June 2013
Last updated 23 July 2021 + show all updates
  1. Added link to new NICE guidelines.

  2. Replaced name 'Clostridium difficile' with 'Clostridioides difficile' to reflect changes in microbial taxonomy.

  3. First published.