Guidance

Clostridioides difficile infection: guidance on management and treatment

Options, agents, recommendations and algorithms for the treatment of Clostridioides difficile (C. difficile) infection.

Published 1 June 2013
Last updated 6 September 2019 — see all updates

• From: Public Health England

Documents

Updated guidance on the management and treatment of C. difficile infection

PDF, 798KB, 29 pages

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Details

This guidance covers:

• a summary of the evidence base and the treatment options for mild, moderate, severe and recurring disease
• description and summary of agents other than metronidazole, vancomycin or fidaxomicin
• recommendations
• treatment algorithms

This document supersedes the relevant sections of Clostridioides difficile infection: How to deal with the problem, published in January 2009.

Published 1 June 2013
Last updated 6 September 2019 + show all updates

1. 6 September 2019

   Replaced name 'Clostridium difficile' with 'Clostridioides difficile' to reflect changes in microbial taxonomy.

2. 1 June 2013

   First published.