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Mpox: guidance

Information and advice for healthcare professionals and the general public.

There are 2 main types (clades) of mpox, clade I and clade II. This page provides further information and guidance for the public, professionals and service providers on clade I and clade II mpox.

Guidance for the public

Guidance on diagnosis and management of mpox cases and contacts

Guidance for non-healthcare settings

Guidance for clade II mpox

Vaccination against mpox

Vaccination against mpox in relation to an outbreak or incident training slide set for healthcare professionals is available for download.

Mpox routine vaccination programme for the protection of GBMSM training slide set for health professionals is available for download.

There is a video of the Intradermal technique for administering the MVA-BN vaccine to view, download and use with the training slide set.

Technical, epidemiological overview, monitoring and surveillance

The UK Health Security Agency (UKHSA) is monitoring the effectiveness and impact of mpox vaccination and disease in the real world:

Effectiveness of one dose of MVA-BN smallpox vaccine against mpox in England using the case-coverage method.

This study estimates the vaccine effectiveness after a single dose of smallpox vaccine against mpox disease.