Following the decline in invasive Hib disease, PHE extended its enhanced surveillance to include all cases of invasive Haemophilus influenzae infections across all age groups in England and Wales (January 2009 onward).
Clinicians, microbiologists and public health doctors can report all cases of invasive H. influenzae infections to PHE respiratory and vaccine preventable bacteria reference unit (RVPBRU) and refer the isolate for confirmation and serotyping if this has not already been done.
PHE also identifies cases reported through the NHS hospital microbiology electronic laboratory reporting system, LabBase2.
A case of H. influenzae infection is considered invasive if the organism was isolated from a normally sterile site, such as blood culture, cerebrospinal fluid (CSF), joint fluid, pleural fluid, or similar.
For all cases, RVPBRU sends an age and gender appropriate questionnaire requesting information on clinical presentation, risk factors, complications and outcome to the patient’s general practitioner (GP), though any clinician can complete the questionnaire.