Health protection – collection

Carbapenem resistance: guidance, data and analysis

The management, surveillance and epidemiology of carbapenem resistance.

Carbapenems are a powerful group of broad spectrum beta-lactam (penicillin-related) antibiotics. In many cases, these are our last effective defence against infections caused by multi-resistant bacteria, such as some strains of Klebsiella pneumoniae and Escherichia coli.

Resistance to carbapenems has emerged and is beginning to spread. New antibiotics need to be developed to counter bacteria with this type of resistance. Hospitals need good infection control to prevent their spread.

Public Health England’s Antimicrobial resistance and healthcare associated infections (AMRHAI) reference unit conducts monitoring and surveillance on antibiotic resistance, and has particular interest in carbapenem-resistant bacteria.


  1. AMRHAI reference unit: reference and diagnostic services

    • Detailed guide


English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR) is designed to develop and maintain robust information and surveillance systems to measure antimicrobial utilisation and its impact on resistance and patient safety in England.

  1. English surveillance programme for antimicrobial utilisation and resistance (ESPAUR) report

    • Research and analysis
  2. Carbapenemase-producing Enterobacteriaceae: laboratory confirmed cases

    • Research and analysis