Social conflict is common in Bolivia and blockades may occur along the main roads. Public transport can be disrupted at very short notice and strikes may result in widespread road blockades, including on roads to and from airports. You should never try to cross a blockade. See Road travel and Road blockades
There is a risk of ‘express kidnappings’. Take care when travelling around Bolivia, particularly when you first arrive. If you take a taxi, use a registered company. See Crime
There is a low threat from terrorism. See Terrorism
Carry a photocopy of your passport, including the personal details, entry stamp and disembarkation card with you at all times in case it is requested by immigration officials or the police. See Local Laws and Customs
Parts of Bolivia, including La Paz are at high altitude. See Health
Take out comprehensive travel and medical insurance before you travel.