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How to register your medical devices with the MHRA for the markets in Great Britain and Northern Ireland.
What you need to do to place a medical device on the Great Britain, Northern Ireland and European Union (EU) markets.
How to get information including patient information leaflets (PILs), details on how the medicine can be used (SmPCs) and scientific reports (PARs).
Guidance on labelling for medicinal products used in clinical trials.
How to apply for a clinical trial including eligibility, phases, model IMPDs, costs and how to make changes to your application.
Sets out medicines that cannot be exported from the UK or hoarded because they are needed for UK patients.
Apply for changes to your marketing authorisation, including minor variations type IA and IB, major variations type II and extensions.
How to notify the MHRA of your intention to carry out a clinical investigation for medical devices.
Comply with good manufacturing practice (GMP) and good distribution practice (GDP), and prepare for an inspection.
Guidance on the safe and effective use of GLP-1 medicines for weight loss and diabetes.
Information on telecare monitoring systems and personal alarms that can help you stay safe and independent at home.
Information about the reproductive risks of taking valproate medicines and the measures in place to reduce potential harm.
A guide to the legislation enabling drug services and others to supply take home naloxone without a prescription to save a life in an emergency.
Change your protocol, update your authorisation, report safety issues, submit safety updates and complete your end-of-trial study report.
Guidance on the collection, verification, and reporting of safety events in clinical trials of an investigational medicinal product.
How to show the MHRA you're meeting good clinical practice (GCP) standards and what to expect from an inspection.
How to contact the MHRA for specific services or enquiries.
Guidance on the various types of modifications that can be made to a clinical trial approval.
How to package medicines for sale and what information you must provide to consumers and healthcare professionals.
How to apply for a clinical trial from 28 April 2026, including eligibility, documentation and registration in a public registry.
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