It is recommended that vaccines are kept cool at all stages of their production, distribution and storage, also known as ‘the cold chain’. Sometimes this ‘cold chain’ is interrupted and the vaccines may get warmer or colder than recommended.
Not all vaccines that have fallen outside the recommended storage temperature need be destroyed - some vaccines can still be used. However, if they are used, they are described as being ‘off-label’ vaccines. This leaflet, for patients and parents who are offered these vaccines, describes what ‘off-label’ means.