Twin pregnancies: second trimester screening for Down’s syndrome

This document explains the procedures for second trimester screening for Down's syndrome (trisomy 21) in women with twin pregnancies.



This publication explains second trimester Down’s syndrome screening for women with twin pregnancies.

It sets out:

  • the prevalence of the condition
  • when the quadruple screening test should be offered
  • the diagnostic testing options

Clinician notes

The document includes a section for clinicians to annotate and insert into a woman’s hand-held maternity notes.