Projects granted during 2014 that have a primary purpose of basic research into the musculoskeletal system.
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This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of basic research into the musculoskeletal system.
The following projects were granted:
- use of tri-axial accelerometers to quantify energies during collision in laying hens (poultry, keel, welfare, production, accelerometer)
- redox pathways in osteoarthritis (redox pathways; osteoarthritis; DMM; mouse)
- musculoskeletal ageing and innervation (loading exercise, muscle, bone, innervations)
- skeletal mechanobiology, remodeling and repair (osteoporosis, osteoarthritis, remodelling, repair, loading)
- action of equine stem cells in tissue regeneration (horse, stem cells, regenerative medicine)
- destruction and regeneration of joints in arthritis (cartilage, bone, arthritis, regeneration, healing)
- animal models for muscular dystrophy (dystroglycan, fukutin related protein, glycosylation, neuromuscular)
- using zebrafish to understand gene function and develop new therapies for cancer (melanoma, cancer, development, imaging, drug-development)
- changing the soil: a new approach to treating arthritis (inflammation, fibroblasts, immune response, arthritis)
- cartilage repair, replacement and regeneration (cartilage repair, replacement and regeneration)
- identifying new targets for treating muscular dystrophy (muscular dystrophy, macrophages, dystroglycan, muscle)
- mechanism of statin induced myopathy (statin, myopathy, exercise)
- genetic basis of skeletal evolution and disease (bone, genetics, development, evolution, disease)
- evolution of locomotion in amphibians (biomechanics, locomotion, amphibians)
- gene therapy for neuromuscular and cardiovascular disease (gene therapy, muscle, heart, disease)
- understanding neuromechanical systems biology (locomotion, motor neuron, mouse, optogenetics, proprioception)
- genetic mechanisms of craniofacial malformation (craniosynostosis, skull, mutation, development, mouse)