Projects granted during 2014 that have a primary purpose of basic research into the gastrointestinal system, including liver.
This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of basic research into the gastrointestinal system, including liver.
The following projects were granted:
- mouse models of intestinal disease (stem cells, epithelium, inflammation)
- characterisation of the enteroendocrine axis (enteroendocrine, diabetes, obesity, GLP-1)
- developing methods to treat liver disease (novel, treatment, bile, production, cells)
- targeted therapeutic interventions for liver disease (liver, inflammation, fibrosis, therapy)
- molecular mechanisms of stem cell activation (stem cells, epithelial, activation)
- Podoplanin-CLEC-2 in inflammatory bowel disease (CLEC-2, Podoplanin, inflammatory bowel disease)
- mouse models of hepatic fibrosis and therapeutics investigation (mouse, hepatic, fibrosis)
- modification of gut function by dietary micronutrient intake (diet, micronutrient, metabolism)
- the microenvironment in organ homeostasis and cancer (liver, skin, cancer, stem cell)
- imaging of stem cells In organ fibrosis models of tissue regeneration (liver, kidney, stem cell, regeneration, imaging)
- study and treatment in liver ischaemia reperfusion (ischaemia:reperfusion; mesenchymal stromal cells; liver)