Guidance

Mpox (monkeypox) vaccination recommendations

Recommendations for the use of pre- and post-exposure vaccination during an mpox incident.

Applies to England

Documents

Recommendations for the use of pre and post exposure vaccination during an mpox incident

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Details

This document includes information on:

  • pre-exposure vaccination for occupational exposure
  • post-exposure vaccination
  • vaccine prescribing and administration
  • consent and record forms
  • Imvanex® patient information leaflet

Further mpox guidance is also available, including information on case definitions and contact tracing.

Published 20 May 2022
Last updated 26 August 2022 + show all updates
  1. Added version 12, removed appendices 2 to 5.

  2. Updated to include the use of intradermal administration for pre and post-exposure use in healthy adults, limiting post-exposure vaccination to children under 5 and immunosuppressed individuals, during periods of limited supply, and further clarification on vaccine eligibility for occupational exposure.

  3. Updated guidance, version 10.

  4. Version 9: updated background and added a link to classification of contacts (appendix 6), along with advice for vaccination and follow-up.

  5. Updated appendix 6 to clarify recommendations for PEP after 14 days since last exposure.

  6. Updated guidance, version 7.

  7. Updated guidance, version 6.7.

  8. Added links to additional monkeypox guidance.

  9. First published.