Gonococcal resistance to antimicrobials surveillance programme report
Data on trends in antimicrobial resistance and decreased susceptibility in gonococcal infection in England and Wales are provided by GRASP.
Applies to England and Wales
Documents
Details
Surveillance of antimicrobial resistance is critical in guiding national treatment guidelines to ensure appropriate patient management. The Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) includes a suite of testing and surveillance systems to detect and monitor antimicrobial resistance in Neisseria (N.) gonorrhoeae and potential treatment failures.
The UK Health Security Agency (UKHSA) reports annually on drug resistance and decreased susceptibility in N. gonorrhoeae in England and Wales and has directly influenced changes in treatment guidelines on 3 occasions. The national gonorrhoea management guideline was updated by the British Association for Sexual Health and HIV (BASHH) in April 2025.
Information on suspected gonorrhoea treatment failures should be reported to UKHSA via the HIV and STI Data Exchange. This has restricted access for authorised users only.
Disseminated gonococcal infection (DGI) is a notifiable disease in England as of April 2025. UKHSA performs enhanced surveillance of DGI. Upon notification, UKHSA will ask reporters to complete an enhanced surveillance questionnaire. Please contact grasp.enquiries@ukhsa.gov.uk (no Personal Identifiable Information (PII)) if advice on case management is needed.
Previous GRASP reports were published by Public Health England.
Updates to this page
-
Added 'GRASP report: data to September 2025' and 'Supplementary information: prediction of ciprofloxacin resistance from whole-genome sequencing data'.
-
Added link to the GRASP 2023 slide set.
-
Added GRASP report: data to August 2024.
-
Added 'GRASP report: data to June 2023' and link to the GRASP 2022 slide set.
-
Added 'GRASP report: data to June 2022' and link to the GRASP 2021 slide set.
-
Added GRASP report: data to June 2021 and slide set.
-
Added ‘GRASP report: data to June 2020’ and link to the slide set.
-
Added ‘GRASP report: data to June 2019’.
-
Added ‘GRASP report: data to May 2018’.
-
Added 'GRASP report: data to June 2017'.
-
Added ‘GRASP report: data up to October 2016’.
-
Added ‘GRASP 2014 report’.
-
First published.