Guidance

Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) protocol

Information and procedural guidance for the national gonococcal surveillance programme.

Applies to England and Wales

Documents

GRASP protocol

Details

Surveillance of antimicrobial resistance is critical in shaping national treatment guidelines to ensure appropriate patient management. The Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP), a national sentinel surveillance programme, was established in 2000 to monitor trends and drifts in susceptibility to antimicrobial agents used for the treatment of gonorrhoea in England and Wales.

This document details the background, objectives and methods of GRASP.

Further data on antimicrobial resistance (AMR) in Neisseria gonorrhoeae is available in the annual GRASP reports.

Updates to this page

Published 1 April 2014
Last updated 13 November 2025 show all updates
  1. Updated the GRASP protocol to reflect changes made to the laboratory and bioinformatics methods used to determine antimicrobial susceptibility and the removal of some antimicrobial agents from the programme.

  2. Updated distribution of clinic and laboratory-specific reports, terminology, and links in the GRASP protocol.

  3. Updated standard operating procedure, terminology, and links in the GRASP protocol.

  4. Updated GRASP protocol.

  5. First published.

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