Guidance

COVID-19 vaccine product information

Updated 25 March 2026

COVID-19 vaccines used in the UK including information on dose, eligible ages, storage, stability and appearance.

Spikevax

Spikevax
LP.8.1
50 micrograms/dose
Moderna
Dose 0.5ml (50 micrograms) by intramuscular injection
Age From 18 years
Number of doses per unit 5 (vial)
Dilution required? No: ready to use
Refrigerated storage Thawed and unopened: up to 30 days at +2°C to +8°C
Room temperature stability Unopened vials may be stored for up to 24 hours up to +25°C
Stability after first puncture [footnote 1] May be stored between +2°C and +25°C; use within 6 hours
Appearance A white to off-white dispersion

Comirnaty 30

Comirnaty 30
LP.8.1
30 micrograms/dose
Pfizer BioNTech
Dose 0.3ml (30 micrograms) by intramuscular injection
Age 12 to 17 years
Number of doses per unit 1 (prefilled syringe)
Dilution required? No: ready to use
Refrigerated storage 12 months at +2°C to +8°C
Room temperature stability Unopened prefilled syringes may be stored for up to 12 hours at temperatures up to +30°C
Stability after first puncture [footnote 1] N/A
Appearance A white to off-white dispersion

Comirnaty 10

Comirnaty 10
LP.8.1
10 micrograms/dose
Pfizer BioNTech
Dose 0.3ml (10 micrograms) by intramuscular injection
Age 5 to 11 years
Number of doses per unit 1 (vial)
Dilution required? No: ready to use once thawed
Refrigerated storage Thawed and unopened: up to 10 weeks at +2°C to +8°C
Room temperature stability Unopened vials may be stored for up to 12 hours at temperatures up
to +30°C
Stability after first puncture [footnote 1] May be stored between +2°C and +30°C; use within 12 hours
Appearance Prior to mixing: the thawed dispersion may contain white to offwhite
opaque amorphous particles
After mixing: clear to slightly opalescent dispersion with no particulates visible

Comirnaty 3

Comirnaty 3
LP.8.1
3 micrograms/dose
Concentrate
Pfizer BioNTech
Dose 0.3ml (3 micrograms) by intramuscular injection
Age From 6 months to 4 years
Number of doses per unit 3 (vial)
Dilution required? Yes with 1.1ml sodium chloride 0.9% solution for injection
Refrigerated storage Thawed and unopened: up to 10 weeks at +2°C to +8°C
Room temperature stability Unopened vials may be stored for up to 12 hours at temperatures up
to +30°C
Stability after first puncture [footnote 1] May be stored between +2°C and +30°C; use within 12 hours
Appearance Prior to dilution: the thawed dispersion may contain white to offwhite
opaque amorphous particles
Diluted vaccine: clear to slightly opalescent dispersion with no particulates visible

Nuvaxovid

Nuvaxovid
JN.1
5 micrograms/dose
Sanofi
Dose 0.5ml (5 micrograms) by intramuscular injection
Age Follow Green Book and NHS guidance
Number of doses per unit 1 (prefilled syringe)
Dilution required? No: ready to use
Refrigerated storage Up to 9 months at +2°C to +8°C
Room temperature stability Data not available: remove syringes from the vaccine fridge just before use
Stability after first puncture [footnote 1] N/A
Appearance A colourless to slightly yellow, clear to mildly opalescent disperson free from visible particles

All products except Nuvaxovid contain Polyethylene Glycol (PEG); Nuvaxovid contains Polysorbate 80.

All vaccines should be used in accordance with Green Book and NHS England operational guidance.

Further information on the COVID-19 vaccination programme is available in the COVID-19 Green Book.

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  1. Use as soon as possible to minimise the risk of microbial contamination.  2 3 4 5