Guidance

COVID-19 vaccine product information

Updated 10 April 2024

COVID-19 vaccines [footnote 1] used in the UK including information on dose, eligible ages, storage, stability and appearance.

Comirnaty 3

Comirnaty 3
Omicron XBB.1.5
3 micrograms/dose
Concentrate
Pfizer BioNTech
Dose 0.2ml (3 micrograms) by intramuscular injection.
Age From 6 months to 4 years.
Number of doses per vial 10
Dilution required? Yes with 2.2ml sodium chloride 0.9% solution for injection.
Refrigerated storage Thawed, unopened and undiluted: up to 10 weeks at +2°C to +8°C.
Room temperature stability Unopened vials may be stored for up to 12 hours at temperatures up to +30°C.
Stability after first puncture [footnote 2] May be stored between +2°C and +30°C; use within 12 hours.
Appearance Prior to dilution: the thawed dispersion may contain white to off-white opaque amorphous particles.

Diluted vaccine: white to off-white dispersion, no particulates visible.

Comirnaty 10

Comirnaty 10
Omicron XBB.1.5
10 micrograms/dose
Pfizer BioNTech
Dose 0.3ml (10 micrograms) by intramuscular injection.
Age 5 to 11 years.
Number of doses per vial 6
Dilution required? No: ready to use once thawed.
Refrigerated storage Thawed and unopened: up to 10 weeks at +2°C to +8°C.
Room temperature stability Unopened vials may be stored for up to 12 hours at temperatures up to +30°C.
Stability after first puncture [footnote 2] May be stored between +2°C and +30°C; use within 12 hours.
Appearance Prior to mixing: the thawed dispersion may contain white to off-white opaque amorphous particles.

After mixing: clear to slightly opalescent dispersion with no particulates visible.

Comirnaty 30

Comirnaty 30
Omicron XBB.1.5
30 micrograms/dose
Pfizer BioNTech
Dose 0.3ml (30 micrograms) by intramuscular injection.
Age From 12 years.
Number of doses per vial 6
Dilution required? No: ready to use once thawed.
Refrigerated storage Thawed and unopened: up to 10 weeks at +2°C to +8°C.
Room temperature stability Unopened vials may be stored for up to 12 hours at temperatures up to +30°C.
Stability after first puncture [footnote 2] May be stored between +2°C and +30°C; use within 12 hours.
Appearance Prior to mixing: the thawed dispersion may contain white to off-white opaque amorphous particles.

After mixing: a white to off-white dispersion with no particulates visible.

Spikevax

Spikevax
Omicron XBB.1.5
50 micrograms/dose
Moderna
Dose 0.5ml (50 micrograms) by intramuscular injection.
Age From 18 years.
Number of doses per vial 5
Dilution required? No: ready to use once thawed.
Refrigerated storage Thawed and unopened: up to 30 days at +2°C to +8°C.
Room temperature stability Unopened vials may be stored at +8°C to +25°C up to 24 hours.
Stability after first puncture [footnote 2] May be stored between +2°C and +25°C; use within 6 hours.
Appearance White to off-white dispersion.

All vaccines should be used in accordance with Green Book and NHS England operational guidance.

Further information on the COVID-19 vaccination programme is available in the COVID-19 Green Book, chapter 14a.

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  1. All products contain Polyethylene Glycol (PEG). 

  2. Punctured vials should be used as soon as possible to minimise the risk of microbial contamination.  2 3 4