Health protection – collection

Lyme disease: guidance, data and analysis

The characteristics, diagnosis, management, surveillance and epidemiology of Lyme disease or Lyme borreliosis.

Lyme disease is transmitted by the bite of an infected tick and most commonly appears as a rash around the bite area (erythema migrans). In the UK, about a third of cases do not have a rash and may present with fever, headache or neurological symptoms.

The disease can be found over most of the UK and is common in mainland Europe and the United States.

PHE provides specialist diagnostic services and advice for clinicians through the Rare and Imported Pathogens Laboratory (RIPL). Advice for patients is available on NHS Choices and from Lyme Disease Action.

Management and treatment

  1. Tick bite risks and prevention of Lyme disease: factsheet

    • 2 April 2013
    • Promotional material
  2. Lyme disease: diagnosis and treatment

    • 17 March 2014
    • Guidance


Lyme borreliosis is monitored in England and Wales through passive and enhanced surveillance.

  1. Lyme borreliosis epidemiology

    • 1 May 2013
    • Guidance