Lyme disease: guidance, data and analysis

The characteristics, diagnosis, management, surveillance and epidemiology of Lyme disease or Lyme borreliosis.

Lyme disease is transmitted by the bite of an infected tick and most commonly appears as a rash around the bite area (erythema migrans). In the UK, about a third of cases do not have a rash and may present with fever, headache or neurological symptoms.

The disease can be found over most of the UK and is common in mainland Europe and the United States.

PHE provides specialist diagnostic services and advice for clinicians through the Rare and Imported Pathogens Laboratory (RIPL).

PHE’s advice for patients is available on NHS Choices (reviewed and updated in March 2015). Support and advice is also available from Lyme Disease Action.

Management and treatment

  1. Lyme disease: diagnosis and treatment

    • Guidance
  2. Lyme disease: signs and symptoms

    • Promotional material
  3. Tick bite risks and prevention of Lyme disease: resources

    • Guidance


Lyme borreliosis is monitored in England and Wales through passive and enhanced surveillance. Data are published quarterly in the zoonoses section of the Health Protection Report.

  1. Lyme borreliosis epidemiology

    • Guidance
Published 6 July 2014
Last updated 21 August 2015 + show all updates
  1. Added Lyme disease: signs and symptoms to collection.
  2. First published.