Collection

Extended-spectrum beta-lactamases (ESBLs): guidance, data, analysis

The diagnosis, management and surveillance of extended-spectrum beta-lactamases (ESBLs).

• From: Public Health England
• Published: 1 July 2014

Bacteria that produce enzymes called extended-spectrum beta-lactamases (ESBLs) are resistant to many penicillin and cephalosporin antibiotics and often to other types of antibiotic.

The 2 main bacteria that produce ESBLs are Escherichia coli (E. coli) and Klebsiella species. The ESBLs that E. coli most often produce are called CTX-M enzymes.

E. coli with ESBLs may cause urinary tract infections (UTIs) that can sometimes progress to more serious infections like blood poisoning, which can be life threatening. Resistance makes these infections more difficult to treat.

Diagnosis, management and surveillance

• Extended-spectrum beta-lactamases (ESBLs): treatment, prevention, surveillance
  • 1 December 2013
  • Guidance

Published 1 July 2014