Drug Safety Update

The product information has been updated for all domperidone products, to include a contraindication for patients with confirmed or suspected phaeochromocytoma (a rare tumour of the adrenal gland), due to the risk of episode…

• Therapeutic area: Cardiovascular disease and lipidology and 6 others
• Published: 21 July 2026

Healthcare professionals should be aware of the potential for delayed onset of angioedema and the distinction between bradykinin- and histamine-mediated cases, as treatment strategies differ significantly and bradykinin-medi…

• Therapeutic area: Cardiovascular disease and lipidology and 4 others
• Published: 16 June 2026

The MHRA has reviewed the evidence for finasteride and dutasteride and the risk of suicidal thoughts and behaviours and has recommended further measures to minimise this risk.

• Therapeutic area: Dermatology and 7 others
• Published: 11 May 2026

There have been reports of worsening nasal congestion (rebound congestion) when the effects of nasal decongestant sprays or drops containing xylometazoline hydrochloride and oxymetazoline hydrochloride, wear off.

• Therapeutic area: Dispensing GP practices and 5 others
• Published: 30 April 2026

A falsified version of Mounjaro (tirzepatide) KwikPen 15mg solution for injection has been found supplied through one online pharmacy in the UK. The falsified product is labelled with batch D873576 and applies to Mounjaro Kw…

• Therapeutic area: Dispensing GP practices and 5 others
• Published: 24 February 2026

Non-arteritic anterior ischemic optic neuropathy (NAION), a condition that can cause sudden deterioration in vision, usually in one eye at a time, has been very rarely reported in association with semaglutide in the treatmen…

• Therapeutic area: Emergency medicine and 5 others
• Published: 5 February 2026

The product information for all Glucagon-Like Peptide-1 (GLP-1) receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonists has been further updated to highlight the potential risk o…

• Therapeutic area: Emergency medicine and 5 others
• Published: 29 January 2026

Idiopathic intracranial hypertension (IIH) has been very rarely reported in patients treated with mesalazine. Following a recent review, warnings for IIH are being added to the product information for all mesalazine products…

• Therapeutic area: Emergency medicine and 4 others
• Published: 4 December 2025

The annual #MedSafetyWeek campaign takes place from 3 to 9 November 2025. This year’s campaign theme is ‘we can all help make medicines safer.’

• Therapeutic area: Anaesthesia and intensive care and 39 others
• Published: 23 October 2025

Patients should be reminded and reassured that there is no evidence that taking paracetamol during pregnancy causes autism in children. Paracetamol is recommended as the first-choice pain reliever for pregnant women, used at…

• Therapeutic area: Anaesthesia and intensive care and 34 others
• Published: 23 September 2025