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A statement from the Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (COM).
COM position statement on the COM assessment of in vitro genotoxicity of titanium dioxide.
Introduction Titanium dioxide has been the subject of multiple safety…
The principal assessment of literature was based on the references used in…
Titanium dioxide has been the subject of multiple safety evaluations…
Tier 1. Nanomaterial and generic study design When assessing papers based…
Note: some papers assessed several endpoints. ‘Green’ papers –…
‘Green’ papers – MN assay Donner and others (2016) reported the results of…
COM recommendations for an evaluation of genotoxicity using (Q)SAR models.
Statement on quantitative assessment of genotoxicity data by the Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (COM).
This paper presents guidance on genotoxicity testing strategies for germ cell mutagens.
Guidance from the Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (COM).
Guidance on a strategy for genotoxicity testing and mutagenic hazard assessment of impurities in chemical substances.
Five guidance statements on testing chemicals with no or inadequate genotoxicity data.
Guidance on the role of mutagenic chemicals in cancer and inherited genetic disease.
This paper discusses the use of 3D models in genotoxicity testing.
Covers in vivo biomarkers of genotoxicity that can be used for human carcinogenicity risk assessment. COM guidance statement (G10).
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