Assessment of thresholds for in vivo mutagens

Guidance from the Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (COM).


Guidance statement: thresholds for in vivo mutagens

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A guidance statement providing definitions relating to:

  • thresholds for in vivo mutagens
  • examples of substances where a threshold mode of genotoxicity has been agreed
  • approaches to the determination of threshold doses for in vivo genotoxins
Published 1 April 2010