Yellow fever: the green book, chapter 35

Yellow fever immunisation information for public health professionals, including updates.


Yellow fever: the green book, chapter 35

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Yellow fever is an acute flavivirus infection spread by the bite of an infected mosquito.

This chapter has been updated to reflect the recommendations of the Commission on Human Measures (CHM) to strengthen measures to minimise the potential risk of rare but serious and fatal adverse events associated with yellow fever vaccination (in those with weakened immune systems, those aged 60 years or older and anyone who has had their thymus removed).

Chapter 35 update patches archive

It has been updated in line with the CHM, see the joint letter issued by the MHRA, Public Health England (now UK Health Security Agency), HPS and NaTHNaC which gives further detail.

Published 20 March 2013
Last updated 13 January 2020 + show all updates
  1. Updated with revised chapter.

  2. Added yellow fever vaccine guidance for those with weakened immune systems, those over 60 years and anyone who has had their thymus removed.

  3. Added revised chapter: contraindication section updated for thymectomy and incidental thymectomy.

  4. Added updated section on Yellow fever vaccination indications for patients with immunosuppression and or HIV infection.

  5. Clarified requirements for yellow fever vaccination and International Health Regulations (IHR) regarding certification and duration of protection.

  6. An extensively updated chapter with the addition of a new flow chart showing those who need reinforcing immunisation.

  7. Added new address for Health Protection Scotland Travel Health Section.

  8. Updated the Body text to include a link to National Archives (chapter update patches) and NHS Choices.

  9. First published.