Tuberculosis (TB): molecular diagnosis

Guidance for healthcare professionals about using molecular tests to investigate suspected cases of tuberculosis (TB).


Molecular diagnosis of tuberculosis: Information for healthcare professionals

This file may not be suitable for users of assistive technology.

Request an accessible format.
If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email Please tell us what format you need. It will help us if you say what assistive technology you use.


This guidance provides information on molecular tests and their role in the diagnosis of active TB.

Laboratories can diagnose TB in a number of ways. Laboratory tests can either support or confirm clinical symptoms of TB. The current standard is a positive mycobacterial culture from a body fluid or tissue.

Published 23 July 2014
Last updated 7 January 2016 + show all updates
  1. Updated guidance attached.

  2. First published.