Guidance
Complete routine immunisation schedule from 1 July 2025
Updated 3 June 2025
Routine immunisation programmes
Age due | Vaccines that protect against | Vaccine given | Trade name | Usual site [note 1] | |
---|---|---|---|---|---|
8 weeks old | Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B | DTaP/IPV/Hib/HepB (6 in 1 vaccine) | Infanrix hexa or Vaxelis | Thigh | |
Meningococcal group B (MenB) | MenB | Bexsero | Thigh | ||
Rotavirus gastroenteritis | Rotavirus | Rotarix [note 2] | By mouth | ||
12 weeks old | Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B | DTaP/IPV/Hib/HepB (6 in 1 vaccine) | Infanrix hexa or Vaxelis | Thigh | |
MenB | MenB | Bexsero | Thigh | ||
Rotavirus | Rotavirus | Rotarix [note 2] | By mouth | ||
16 weeks old | Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B | DTaP/IPV/Hib/HepB (6 in 1 vaccine) | Infanrix hexa or Vaxelis | Thigh | |
Pneumococcal (13 serotypes) • if received pneumococcal at 12 weeks give Men B |
PCV | Prevenar 13 | Thigh |
One year old (on or after the child’s first birthday) | Born before 1 July 2024 | Born on or after 1 July 2024 | |||
---|---|---|---|---|---|
Pneumococcal | Pneumococcal | PCV | Prevenar 13 | Upper arm or thigh | |
Measles, mumps, rubella | Measles, mumps, rubella | MMR | MMRvaxPro or Priorix | ||
MenB | MenB | MenB | Bexsero | ||
Hib/MenC (if Hib/MenC exhausted give DTaP/Hib/IPV/HepB) | Hib/MenC | Menitorix |
18 months old | Born before 1 July 2024 | Born on or after 1 July 2024 | |||
---|---|---|---|---|---|
No appointment | DTaP/IPV/Hib/HepB | DTaP/IPV/Hib/HepB | Infanrix hexa or Vaxelis | Upper arm or thigh | |
Measles, mumps, rubella | MMR | MMRvaxPro or Priorix | |||
3 years 4 months old or soon after | Born before 1 July 2024 | Born on or after 1 July 2024 | |||
Diphtheria, tetanus, pertussis and polio | Diphtheria, tetanus, pertussis and polio | dTaP/IPV | REPEVAX | Upper arm or thigh | |
Measles, mumps, rubella | MMR | MMRvaxPro or Priorix |
Age due | Vaccines that protect against | Vaccine given | Trade name | Usual site [footnote 1] |
---|---|---|---|---|
Boys and girls aged 12 to 13 years | Cancers and genital warts caused by specific human papillomavirus (HPV) types | HPV | Gardasil 9 | Upper arm |
14 years old (school Year 9) | Tetanus, diphtheria and polio | Td/IPV | REVAXIS | Upper arm |
Meningococcal groups A, C, W and Y | MenACWY | MenQuadfi | Upper arm | |
Eligible paediatric age group See annual flu letter (each year from September) |
Influenza |
LAIV (Live attenuated influenza vaccine) • If LAIV is contraindicated or otherwise unsuitable use inactivated flu vaccine (check Green Book chapter 19 for details) |
Fluenz (contains porcine gelatine) | Both nostrils |
65 years old | Pneumococcal (23 serotypes) | Pneumococcal polysaccharide vaccine (PPV23) | Pneumovax 23 | Upper arm |
65 years of age and older | Influenza (each year from September) | Inactivated influenza vaccine | Multiple | Upper arm |
65 from September 2023 ) | Shingles | Shingles vaccine | Shingrix | Upper arm |
70 to 79 years of age (plus eligible age groups and severely immunosuppressed) | Shingles | Shingles vaccine | Zostavax (or Shingrix if Zostavax contraindicated) |
Upper arm |
75 years old | Respiratory syncytial virus (RSV) | RSV vaccine | Abrysvo | Upper arm |
Notes
- Intramuscular injection into deltoid muscle in upper arm or anterolateral aspect of the thigh.
- Rotavirus vaccine should only be given after checking for SCID screening result.
Selective immunisation programmes
Target group | Age and schedule | Disease | Vaccines required | |
---|---|---|---|---|
Babies born to women with hepatitis B infection [note 1], [note 2 | At birth, 4 weeks if born before 01 July 2024 give additional dose at 12 months old [note 1] |
Hepatitis B | Hepatitis B (Engerix B/HBvaxPRO) | |
Infants in areas of the country with tuberculosis (TB) incidence >= 40/100,000 | Around 28 days old [note 4] | Tuberculosis | BCG | |
Infants with a parent or grandparent born in a high incidence country [note3] | Around 28 days old [note 4] | Tuberculosis | BCG | |
Children in a clinical risk group | Age under 2 years • if first ever flu vaccine give second dose at 4 weeks |
Influenza | inactivated flu vaccine | |
Age under 2 years • if first ever flu vaccine give second dose at 4 weeks |
Influenza | LAIV or inactivated flu vaccine if contraindicated to LAIV | ||
Age 9 to 17 years • one dose required each flu season |
Influenza | LAIV or inactivated flu vaccine if contraindicated to LAIV | ||
Pregnant women | At any stage of pregnancy during flu season | Influenza | Inactivated flu vaccine | |
From 16 weeks gestation [note 5] | Pertussis | Tdap (ADACEL) | ||
From 28 weeks gestation | RSV | RSV vaccine (Abrysvo) |
Notes
- Take blood for HBsAg on or after 12 months to exclude infection. For children born on or after 1 July 2024, test anytime between 12 and 18 months.
- In addition hexavalent vaccine (Infanrix hexa or Vaxelis) is given at 8, 12 and 16 weeks and, for children born on or after 1 July 2024, also at 18 months.
- Where the annual incidence of TB is 40 per 100,000 or higher – see TB incidence by country.
- Check SCID screening outcome before giving BCG.
- Ideally before 32 weeks gestation but may still be given after 32 weeks.
Additional vaccines for individuals with underlying medical conditions
Medical condition | Diseases protected against | Vaccines required [note 1] |
---|---|---|
Asplenia or splenic dysfunction (this also includes individuals with coeliac disease who are diagnosed with splenic dysfunction and all haemoglobinopathies including homozygous sickle cell disease) |
Meningococcal groups A, B, C, W and Y |
MenACWY MenB |
Pneumococcal |
PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age) |
|
Influenza | Annual flu vaccine | |
Cochlear implants | Pneumococcal |
PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age) |
Chronic respiratory and heart conditions (such as severe asthma, chronic pulmonary disease, and heart failure) | Pneumococcal |
PCV13 (up to 10 years of age)[note 2] PPV23 (from 2 years of age) |
Influenza | Annual flu vaccine | |
Chronic neurological conditions | Pneumococcal (only if the individual is also at increased risk of aspiration) |
PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age) |
Influenza | Annual flu vaccine | |
Diabetes | Pneumococcal |
PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age) |
Influenza | Annual flu vaccine | |
Chronic kidney disease (CKD) (including haemodialysis) | Pneumococcal (stage 4 and 5 CKD) |
PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age) |
Influenza (stage 3, 4 and 5 CKD) | Annual flu vaccine | |
Hepatitis B (stage 4 and 5 CKD) | Hepatitis B | |
Chronic liver conditions | Pneumococcal |
PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age) |
Influenza | Annual flu vaccine | |
Hepatitis A | Hepatitis A | |
Hepatitis B | Hepatitis B | |
Haemophilia | Hepatitis A | Hepatitis A |
Hepatitis B | Hepatitis B | |
Immunosuppression due to disease or treatment [note 4] | Pneumococcal |
PCV13 (up to 10 years of age) [note 2] ,[note 3] PPV23 (from 2 years of age) |
Shingles vaccine | Shingrix – over 50 years of age [note 5] | |
Influenza | Annual flu vaccine | |
Complement disorders (including those receiving complement inhibitor therapy) | Meningococcal groups A, B, C, W and Y |
MenACWY MenB |
Pneumococcal |
PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age |
|
Influenza | Annual flu vaccine |
Notes
- Check relevant chapter of the Green Book for specific schedule.
- If aged 2 years to under 10 years of age and unimmunised or partially immunised against pneumococcal infection, give one PCV13 dose.
- To any age in severely immunosuppressed.
- Consider annual influenza vaccination for household members and those who care for people with these conditions.
- Check Green Book Shingles Chapter 28a www.gov.uk/government/publications/ shingles-herpes-zoster-the-green-book-chapter-28a