Guidance

Complete routine immunisation schedule from 1 July 2025

Updated 3 June 2025

Routine immunisation programmes

Age due	Vaccines that protect against	Vaccine given	Trade name	Usual site [note 1]
8 weeks old	Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B	DTaP/IPV/Hib/HepB (6 in 1 vaccine)	Infanrix hexa or Vaxelis	Thigh
	Meningococcal group B (MenB)	MenB	Bexsero	Thigh
	Rotavirus gastroenteritis	Rotavirus	Rotarix [note 2]	By mouth
12 weeks old	Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B		DTaP/IPV/Hib/HepB (6 in 1 vaccine)	Infanrix hexa or Vaxelis	Thigh
	MenB	MenB	Bexsero	Thigh
	Rotavirus	Rotavirus	Rotarix [note 2]	By mouth
16 weeks old	Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B	DTaP/IPV/Hib/HepB (6 in 1 vaccine)	Infanrix hexa or Vaxelis	Thigh
	Pneumococcal (13 serotypes) • if received pneumococcal at 12 weeks give Men B		PCV	Prevenar 13	Thigh

One year old (on or after the child’s first birthday)	Born before 1 July 2024	Born on or after 1 July 2024
	Pneumococcal	Pneumococcal	PCV	Prevenar 13	Upper arm or thigh
	Measles, mumps, rubella	Measles, mumps, rubella	MMR	MMRvaxPro or Priorix
	MenB	MenB	MenB	Bexsero
	Hib/MenC (if Hib/MenC exhausted give DTaP/Hib/IPV/HepB)		Hib/MenC	Menitorix

18 months old	Born before 1 July 2024	Born on or after 1 July 2024
	No appointment	DTaP/IPV/Hib/HepB	DTaP/IPV/Hib/HepB	Infanrix hexa or Vaxelis	Upper arm or thigh
		Measles, mumps, rubella	MMR	MMRvaxPro or Priorix
3 years 4 months old or soon after	Born before 1 July 2024	Born on or after 1 July 2024
	Diphtheria, tetanus, pertussis and polio	Diphtheria, tetanus, pertussis and polio	dTaP/IPV	REPEVAX	Upper arm or thigh
	Measles, mumps, rubella		MMR	MMRvaxPro or Priorix

Age due	Vaccines that protect against	Vaccine given	Trade name	Usual site [footnote 1]
Boys and girls aged 12 to 13 years	Cancers and genital warts caused by specific human papillomavirus (HPV) types	HPV	Gardasil 9	Upper arm
14 years old (school Year 9)	Tetanus, diphtheria and polio	Td/IPV	REVAXIS	Upper arm
	Meningococcal groups A, C, W and Y	MenACWY	MenQuadfi	Upper arm
Eligible paediatric age group See annual flu letter (each year from September)	Influenza	LAIV (Live attenuated influenza vaccine) • If LAIV is contraindicated or otherwise unsuitable use inactivated flu vaccine (check Green Book chapter 19 for details)	Fluenz (contains porcine gelatine)	Both nostrils
65 years old	Pneumococcal (23 serotypes)	Pneumococcal polysaccharide vaccine (PPV23)	Pneumovax 23	Upper arm
65 years of age and older	Influenza (each year from September)	Inactivated influenza vaccine	Multiple	Upper arm
65 from September 2023 )	Shingles	Shingles vaccine	Shingrix	Upper arm
70 to 79 years of age (plus eligible age groups and severely immunosuppressed)	Shingles	Shingles vaccine	Zostavax  (or Shingrix if Zostavax contraindicated)	Upper arm
75 years old	Respiratory syncytial virus (RSV)	RSV vaccine	Abrysvo	Upper arm

Notes

1. Intramuscular injection into deltoid muscle in upper arm or anterolateral aspect of the thigh.
2. Rotavirus vaccine should only be given after checking for SCID screening result.

Selective immunisation programmes

Target group	Age and schedule	Disease	Vaccines required
Babies born to women with hepatitis B infection  [note 1], [note 2	At birth, 4 weeks if born before 01 July 2024 give additional dose at 12 months old [note 1]	Hepatitis B	Hepatitis B (Engerix B/HBvaxPRO)
Infants in areas of the country with tuberculosis (TB) incidence >= 40/100,000	Around 28 days old [note 4]	Tuberculosis	BCG
Infants with a parent or grandparent born in a high incidence country [note3]	Around 28 days old [note 4]	Tuberculosis	BCG
Children in a clinical risk group	Age under 2 years • if first ever flu vaccine give second dose at 4 weeks	Influenza	inactivated flu vaccine
	Age under 2 years • if first ever flu vaccine give second dose at 4 weeks	Influenza	LAIV or inactivated flu vaccine if contraindicated to LAIV
	Age 9 to 17 years • one dose required each flu season	Influenza	LAIV or inactivated flu vaccine if contraindicated to LAIV
Pregnant women	At any stage of pregnancy during flu season	Influenza	Inactivated flu vaccine
	From 16 weeks gestation [note 5]	Pertussis	Tdap (ADACEL)
	From 28 weeks gestation	RSV	RSV vaccine (Abrysvo)

Notes

1. Take blood for HBsAg on or after 12 months to exclude infection. For children born on or after 1 July 2024, test anytime between 12 and 18 months.
2. In addition hexavalent vaccine (Infanrix hexa or Vaxelis) is given at 8, 12 and 16 weeks and, for children born on or after 1 July 2024, also at 18 months.
3. Where the annual incidence of TB is 40 per 100,000 or higher – see TB incidence by country.
4. Check SCID screening outcome before giving BCG.
5. Ideally before 32 weeks gestation but may still be given after 32 weeks.

Additional vaccines for individuals with underlying medical conditions

Medical condition	Diseases protected against	Vaccines required [note 1]
Asplenia or splenic dysfunction  (this also includes individuals with coeliac disease who are diagnosed with splenic dysfunction and all haemoglobinopathies including homozygous sickle cell disease)	Meningococcal groups A, B, C, W and Y	MenACWY MenB
	Pneumococcal	PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age)
	Influenza	Annual flu vaccine
Cochlear implants	Pneumococcal	PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age)
Chronic respiratory and heart conditions (such as severe asthma, chronic pulmonary disease, and heart failure)	Pneumococcal	PCV13 (up to 10 years of age)[note 2] PPV23 (from 2 years of age)
	Influenza	Annual flu vaccine
Chronic neurological conditions	Pneumococcal (only if the individual is also at increased risk of aspiration)	PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age)
	Influenza	Annual flu vaccine
Diabetes	Pneumococcal	PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age)
	Influenza	Annual flu vaccine
Chronic kidney disease (CKD) (including haemodialysis)	Pneumococcal (stage 4 and 5 CKD)	PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age)
	Influenza (stage 3, 4 and 5 CKD)	Annual flu vaccine
	Hepatitis B (stage 4 and 5 CKD)	Hepatitis B
Chronic liver conditions	Pneumococcal	PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age)
	Influenza	Annual flu vaccine
	Hepatitis A	Hepatitis A
	Hepatitis B	Hepatitis B
Haemophilia	Hepatitis A	Hepatitis A
	Hepatitis B	Hepatitis B
Immunosuppression due to disease or treatment [note 4]	Pneumococcal	PCV13 (up to 10 years of age) [note 2] ,[note 3] PPV23 (from 2 years of age)
	Shingles vaccine	Shingrix – over 50 years of age [note 5]
	Influenza	Annual flu vaccine
Complement disorders (including those receiving complement inhibitor therapy)	Meningococcal groups A, B, C, W and Y	MenACWY MenB
	Pneumococcal	PCV13 (up to 10 years of age) [note 2] PPV23 (from 2 years of age
	Influenza	Annual flu vaccine

Notes

1. Check relevant chapter of the Green Book for specific schedule.
2. If aged 2 years to under 10 years of age and unimmunised or partially immunised against pneumococcal infection, give one PCV13 dose.
3. To any age in severely immunosuppressed.
4. Consider annual influenza vaccination for household members and those who care for people with these conditions.
5. Check Green Book Shingles Chapter 28a www.gov.uk/government/publications/ shingles-herpes-zoster-the-green-book-chapter-28a