Guidance

Routine childhood immunisations from 1 July 2025 (babies born from 1 July 2024)

Updated 3 June 2025

Routine childhood immunisations

Age due Vaccines that protect against Vaccine given Trade name Usual site [footnote 1]
8 weeks old Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B
  DTaP/IPV/Hib/HepB (6 in 1 vaccine)
Infanrix hexa or Vaxelis
Thigh
  Meningococcal group B (MenB)
  MenB
Bexsero
Thigh
  Rotavirus gastroenteritis   Rotavirus Rotarix [footnote 2] By mouth
12 weeks old Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B
  DTaP/IPV/Hib/HepB (6 in 1 vaccine)
Infanrix hexa or Vaxelis
Thigh
  MenB
  MenB
Bexsero
Thigh
  Rotavirus   Rotavirus Rotarix [footnote 2] By mouth
16 weeks old Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B
  DTaP/IPV/Hib/HepB (6 in 1 vaccine)
Infanrix hexa or Vaxelis
Thigh
  Pneumococcal (13 serotypes)
• if received pneumococcal at 12 weeks give Men B
  PCV Prevenar 13 Thigh
One year old (on or after the child’s first birthday) Born before 1 July 2024
Born on or after 1 July 2024



  Pneumococcal
Pneumococcal
PCV
Prevenar 13
Upper arm or thigh
  Measles, mumps, rubella
Measles, mumps, rubella
MMR
MMRvaxPro or Priorix
 
  MenB
MenB MenB
Bexsero
 
  Hib/MenC (if Hib/MenC exhausted give DTaP/Hib/IPV/HepB)   Hib/MenC Menitorix  
18 months old Born before 1 July 2024
Born on or after 1 July 2024



  No appointment DTaP/IPV/Hib/HepB
DTaP/IPV/Hib/HepB
Infanrix hexa or Vaxelis
Upper arm or thigh
    Measles, mumps, rubella MMR MMRvaxPro or Priorix  
3 years 4 months old or soon after Born before 1 July 2024
Born on or after 1 July 2024



  Diphtheria, tetanus, pertussis and polio
Diphtheria, tetanus, pertussis and polio dTaP/IPV
REPEVAX
Upper arm or thigh
  Measles, mumps, rubella   MMR MMRvaxPro or Priorix  
Boys and girls aged 12 to 13 years Cancers and genital warts caused by specific human papillomavirus (HPV) types   HPV Gardasil 9 Upper arm
14 years old (school Year 9) Tetanus, diphtheria and polio
  Td/IPV
REVAXIS
Upper arm
  Meningococcal groups A, C, W and Y   MenACWY MenQuadfi Upper arm
Eligible paediatric age group
See annual flu letter
Influenza (each year from September)   LAIV (Live attenuated influenza vaccine)
• If LAIV is contraindicated or otherwise unsuitable use inactivated flu vaccine (check Green Book chapter 19 for details)
Fluenz (contains porcine gelatine) Both nostrils

Selective childhood immunisation programmes

Target group Age and schedule Disease Vaccines required
Babies born to mothers with hepatitis B [footnote 3] At birth, 4 weeks
• if born before 1 July 2024 give additional dose at one year
Hepatitis B Hepatitis B (Engerix B/HBvaxPRO)
Infants in areas of the country with TB incidence >= 40/100,000 Around 28 days old Tuberculosis BCG
Check SCID screening outcome before giving BCG
Infants with a parent or grandparent born in a high incidence country [footnote 4] Around 28 days old Tuberculosis BCG
Check SCID screening outcome before giving BCG
Children in a clinical risk group Age under 2 years
• if first ever flu vaccine give second dose at 4 weeks
Influenza Inactivated flu vaccine
  Aged 2 to 8 years
• if first ever flu vaccine give second dose at 4 weeks
  LAIV
• if LAIV contraindicated or otherwise unsuitable give inactivated flu
  Aged 9 to17 years
• only one dose required each flu season
  LAIV
• if LAIV contraindicated or otherwise unsuitable give inactivated flu
Pregnant women At any stage of pregnancy during flu season
Influenza
Inactivated flu vaccine
  From 16 weeks gestation
Pertussis
Tdap (ADACEL)
  From 28 weeks gestation RSV RSV vaccine (Abrysvo)
  1.    Intramuscular injection into deltoid muscle in upper arm or anterolateral aspect of the thigh. 

  2.   Rotavirus vaccine should only be given after checking for SCID screening result 2

  3.   Take blood for HBsAg on or after 12 months to exclude infection. For children born on or after 1 July 2024, test anytime between 12 and 18 months. 

  4.   Where the annual incidence of TB is >= 40/100,000 – see tuberculosis by country: rates per 100,000 people