Guidance

Routine childhood immunisations from 1 January 2026

Updated 1 December 2025

Routine childhood immunisations

Age due	Diseases that vaccines protect against	Vaccine given	Trade name	Usual site [footnote 1]
8 weeks old	Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B	DTaP/IPV/Hib/HepB (6 in 1 vaccine)	Infanrix hexa or Vaxelis	Thigh
	Meningococcal group B (MenB)	MenB	Bexsero	Thigh
	Rotavirus gastroenteritis	Rotavirus	Rotarix [footnote 2]	By mouth
12 weeks old	Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B	DTaP/IPV/Hib/HepB (6 in 1 vaccine)	Infanrix hexa or Vaxelis	Thigh
	MenB	MenB	Bexsero	Thigh
	Rotavirus	Rotavirus	Rotarix [footnote 2]	By mouth
16 weeks old	Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B	DTaP/IPV/Hib/HepB (6 in 1 vaccine)	Infanrix hexa or Vaxelis	Thigh
	Pneumococcal (13 serotypes)	PCV	Prevenar 13	Thigh
One year old (on or after the child’s first birthday)	Pneumococcal	PCV	Prevenar 13	Upper arm or thigh
	Measles, mumps, rubella and varicella (chickenpox)	MMRV	ProQuad or Priorix Tetra	Upper arm or thigh
	MenB	MenB	Bexsero	Upper arm or thigh
18 months old	Born on or after 1 July 2024 DTaP/IPV/Hib/HepB. Measles, mumps, rubella and varicella Born on or after 30 June 2024 No appointment	DTaP/IPV/Hib/HepB MMRV	Infanrix hexa or Vaxelis ProQuad or Priorix Tetra	Upper arm or thigh
3 years, 4 months old or soon after	Born on or after 1 January 2025 Diphtheria, tetanus, pertussis and polio Born on or after 31 December 2024 Diphtheria, tetanus, pertussis and polio. Measles, mumps, rubella and varicella	dTaP/IPV MMRV	REPEVAX ProQuad or Priorix Tetra	Upper arm or thigh
Boys and girls aged 12 to 13 years	Cancers and genital warts caused by specific human papillomavirus (HPV) types	HPV	Gardasil 9	Upper arm
14 years old (school Year 9)	Tetanus, diphtheria and polio	Td/IPV	REVAXIS	Upper arm
	Meningococcal groups A, C, W and Y	MenACWY	MenQuadfi	Upper arm
Eligible paediatric age group See annual flu letter	Influenza (each year from September)	LAIV (Live attenuated influenza vaccine) – if LAIV is contraindicated or otherwise unsuitable, use inactivated flu vaccine (check Green Book chapter 19 for details)	Fluenz (contains porcine gelatine)	Both nostrils

Selective childhood immunisation programmes

Target group	Age and schedule	Disease	Vaccines required
Babies born to mothers with hepatitis B [footnote 3]	At birth, 4 weeks – if born before 1 July 2024, give additional dose at one year	Hepatitis B	Hepatitis B (Engerix B/HBvaxPRO)
Infants in areas of the country with TB incidence >= 40/100,000	Around 28 days old	Tuberculosis	BCG Check SCID screening outcome before giving BCG
Infants with a parent or grandparent born in a high incidence country [footnote 4]	Around 28 days old	Tuberculosis	BCG Check SCID screening outcome before giving BCG
Children in a clinical risk group	Age under 2 years – if first ever flu vaccine, give second dose at 4 weeks	Influenza	Inactivated flu vaccine
	Aged 2 to 8 years – if first ever flu vaccine, give second dose at 4 weeks		LAIV – if LAIV contraindicated or otherwise unsuitable, give inactivated flu
	Aged 9 to17 years – only one dose required each flu season		LAIV – if LAIV contraindicated or otherwise unsuitable, give inactivated flu
Pregnant women	At any stage of pregnancy during flu season	Influenza	Inactivated flu vaccine
	From 16 weeks gestation	Pertussis	Tdap (ADACEL)
	From 28 weeks gestation	RSV	RSV vaccine (Abrysvo)

1.    Intramuscular injection into deltoid muscle in upper arm or anterolateral aspect of the thigh. ↩

2.   Rotavirus vaccine should only be given after checking for SCID screening result. ↩ ↩²

3.   Take blood for HBsAg on or after 12 months to exclude infection. For children born on or after 1 July 2024, test anytime between 12 and 18 months. ↩

4.   Where the annual incidence of TB is >= 40/100,000 – see tuberculosis by country: rates per 100,000 people. ↩