Non-tech. summaries 2014: projects on the reproductive system
Projects granted during 2014 that have a primary purpose of basic research into the urogenital/reproductive system.
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This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of basic research into the urogenital/reproductive system.
The following projects were granted:
- anti-mullerian hormone immunoassay development (monoclonal immunoassays anti-mullerian hormone)
- mammary gland development, stem cells and breast cancer (cancer, mammary, stem cells, genetics)
- production of fertilised oocytes (xenopus, oocyctes, multisensory, locomotion, CNS)
- neuroendocrine control of reproduction (reproduction, Kisspeptin, GnRH, hypothalamus, pituitary)
- use of a natural biomaterial for hypospadias repair (biomaterial, urinary tract, hypospadias, urethra)
- germline genetic inheritance and reproductive health (fertility; ageing; chromosomes; mitochondria; cancer)
- modelling complications of early pregnancy (pregnancy, miscarriage, ectopic, maternal health)
- cytoplasmic regulation of mRNAs (gene regulation, mRNA translation, post- transcriptional control, RNA-binding protein, translational activators)
- regulation of ion transporters expressed in the kidney (high blood pressure, salt intake, salt excretion, metabolic syndrome)
- nerve growth and regeneration (stimulating nerve growth and guidance)
- mechanisms of meiosis and causes of aneuploidy (meiosis, oocyte, aneuploidy)
- renal inflammation, fibrosis and repair (inflammation, fibrosis, repair)
- investigation of gonadal development (fertility, ovary, testis, embryo)
- fertility control in wildlife (wildlife, fertility control, immunocontraception)
- receptor functions in development and infection (receptors, fertility, pathogens, vaccines)
- oocyte epigenetics: mechanisms and effect of diet (epigenetics, methylation, oocytes, embryos, diet)
- mechanism and functional role of calcium signals (calcium; cell signalling; fertilization; transgenics)
- papillomavirus life-cycle regulation (papillomavirus, epithelium, tropism, warts, regression)