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Non-tech. summaries 2014: projects on the reproductive system

Projects granted during 2014 that have a primary purpose of basic research into the urogenital/reproductive system.

From:
Home Office
Published
25 April 2016

Documents

Non-technical summaries: projects granted in 2014, volume 25

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Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of basic research into the urogenital/reproductive system.

The following projects were granted:

  • anti-mullerian hormone immunoassay development (monoclonal immunoassays anti-mullerian hormone)
  • mammary gland development, stem cells and breast cancer (cancer, mammary, stem cells, genetics)
  • production of fertilised oocytes (xenopus, oocyctes, multisensory, locomotion, CNS)
  • neuroendocrine control of reproduction (reproduction, Kisspeptin, GnRH, hypothalamus, pituitary)
  • use of a natural biomaterial for hypospadias repair (biomaterial, urinary tract, hypospadias, urethra)
  • germline genetic inheritance and reproductive health (fertility; ageing; chromosomes; mitochondria; cancer)
  • modelling complications of early pregnancy (pregnancy, miscarriage, ectopic, maternal health)
  • cytoplasmic regulation of mRNAs (gene regulation, mRNA translation, post- transcriptional control, RNA-binding protein, translational activators)
  • regulation of ion transporters expressed in the kidney (high blood pressure, salt intake, salt excretion, metabolic syndrome)
  • nerve growth and regeneration (stimulating nerve growth and guidance)
  • mechanisms of meiosis and causes of aneuploidy (meiosis, oocyte, aneuploidy)
  • renal inflammation, fibrosis and repair (inflammation, fibrosis, repair)
  • investigation of gonadal development (fertility, ovary, testis, embryo)
  • fertility control in wildlife (wildlife, fertility control, immunocontraception)
  • receptor functions in development and infection (receptors, fertility, pathogens, vaccines)
  • oocyte epigenetics: mechanisms and effect of diet (epigenetics, methylation, oocytes, embryos, diet)
  • mechanism and functional role of calcium signals (calcium; cell signalling; fertilization; transgenics)
  • papillomavirus life-cycle regulation (papillomavirus, epithelium, tropism, warts, regression)
Published 25 April 2016

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