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Research and analysis

Mpox clade Ib and clade IIb outbreak: epidemiological overview

The latest information on mpox clade Ib and clade IIb cases in the UK and mpox vaccine administration in England.

Documents

Mpox outbreak: epidemiological overview, June 2022 to December 2024 (link to UK Government Web Archive)

Details

From September 2026, this report contains the latest national figures for cases of clade Ib, clade IIb, clade not yet known, and recombinant clades of mpox in the UK.

From 11 June 2026, this report also presents data for mpox vaccine administration in England.

Previous reports from February 2025 to August 2026 include data for clade Ib and clade Ib only, with clade not yet known combined into clade IIb case counts.

Mpox is a re-emerging zoonotic infection, caused by the monkeypox virus (MPXV), that occurs mostly in West and Central Africa.

From 21 June 2022 to week ending 5 August 2022, this update was published twice a week (Tuesdays and Fridays) and replaced the news stories previously published 3 times a week. Between 9 August 2022 and 20 December 2022, this report was published weekly on Tuesdays with an accompanying data set showing mpox case numbers by region and upper tier local authority of residence.

From 2 March 2023 onwards, this report has been published monthly to provide the latest national figures for cases of mpox.

Please refer to the UK Health Security Agency (UKHSA) notifications of infectious diseases reports for weekly updates on laboratory-notified mpox cases in England and on notifications of clinically suspected mpox in England and Wales by region and local authority. Further details on the epidemiology are available in the mpox technical briefing.

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