Research and analysis

Monkeypox outbreak: epidemiological overview, 5 July 2022

Updated 4 April 2024

Monkeypox is a zoonotic infection, caused by the monkeypox virus, that occurs mostly in West and Central Africa. Previous cases in the UK had been either imported from countries where monkeypox is endemic or contacts with documented epidemiological links to imported cases. Between 2018 and 2021, there had been 7 cases of monkeypox in the UK. Of these, 4 were imported, 2 were cases in household contacts, and 1 was a case in a health care worker involved in the care of an imported case. There was no documented community transmission in previous outbreaks.

Current epidemiological situation as of 4 July 2022

Cases of monkeypox infection were confirmed in England from 6 May 2022. The outbreak has mainly been in gay, bisexual, and men who have sex with men without documented history of travel to endemic countries. Further details on the epidemiology are available in the monkeypox technical briefing.

Up to 4 July 2022 there were 1,351 laboratory confirmed cases in the UK. Of these, 40 were in Scotland, 11 were in Northern Ireland, 15 were in Wales and 1,285 were in England.

Table 1: Number of laboratory confirmed cases by UK nation of residence, 6 May to 4 July 2022 (n = 1,351)

UK nation Confirmed cases Change since last report (30 June 2022)
England 1,285 +100
Northern Ireland 11 +5
Scotland 40 +6
Wales 15 +5
Total 1,351 +116

A high proportion of England cases were known to be London residents (77%, 867 of 1,128 with reported home address). For confirmed cases in the UK, where gender information was available, 1,273 (100%) confirmed cases were male, with 6 confirmed female cases. The median age of confirmed cases in the UK was 36 years (interquartile range 31 to 43).

Table 2: Number of laboratory confirmed monkeypox cases by region of residence, England, 6 May to 4 July 2022 (n = 1,285)

Region of residence Total confirmed Change since last report (30 June 2022)
East of England 46 +13
East Midlands 12 +1
London 867 +175
North East 10 +3
North West 57 +13
South East 82 +16
South West 17 +3
West Midlands 20 +3
Yorkshire and Humber 17 +3
Under investigation* 157 -130
Total 1,285 +100

*Address not yet confirmed

Data sources

Monkeypox surveillance data in England is currently compiled daily, based on monkeypox virus test results from the Rare and Imported Pathogens Laboratory (RIPL) in the UK Health Security Agency (UKHSA). This is combined with case information recorded by local Health Protection Teams in the UKHSA national case management system.

Counts of confirmed cases in Wales, Northern Ireland, and Scotland are submitted to UKHSA by Public Health Wales, Public Health Agency Northern Ireland, and Public Health Scotland respectively.

Information about this publication

This update is currently published on Tuesdays and Fridays, using data extracted by 9.30am on Mondays and Thursdays. As of 21 June 2022, this report replaces the UKHSA news stories previously published 3 times a week.

These figures are used for official reporting of monkeypox confirmed case counts in the UK.

England counts may differ from those published in the Notifications of infectious diseases (NOIDs) causative agents weekly report. This is due to differences in timings of when the data is compiled, and differences in processing of duplicate data (for example, if a person has tested more than once but insufficient information is provided to identify them).

Additional resources

Monkeypox technical briefings.

Monkeypox: Case Definitions. Published: 20 May 2022; Updated: 24 May 2022.

Monkeypox contact tracing guidance: classification of contacts and advice for vaccination and follow-up. Published: 20 May 2022.