Research and analysis

Monitoring by nose blow sampling

This investigation (HPA-CRCE-030) describes the potential for developing nose blow sampling into a screening method for exposure to radionuclides.



Nose blow sampling is used to identify people who may have radionuclide intakes. Such monitoring had shown that the activities cleared by nose blows produced on-demand have little relationship to the intake size.

In contrast, a human volunteer study of nasal deposition and clearance had found that the activities of nose blow samples produced are related to the activity initially deposited in the extra-thoracic (ET) airways which depends on the time between intake and nose blow.

A pilot study investigated if a method of nose blow sampling could be developed to give a simple estimate of the quantity of a suspected intake, and resolve differences between the volunteer study findings and the results of occupational monitoring.