Guidance

Influenza: treatment and prophylaxis using anti-viral agents

Guidance on how to manage influenza (flu) using anti-viral agents.

Documents

PHE guidance on use of antiviral agents for the treatment and prophylaxis of influenza

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The use of antivirals for the treatment and prophylaxis of influenza: summary of guidance for healthcare professionals

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Letter to clinicians regarding the use of antivirals in influenza

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Details

This guidance covers:

  • definitions
  • treatment of suspected or confirmed influenza
  • post-exposure prophylaxis supply of zanamivir acqueous solution
  • use of anti-virals in pregnancy, breastfeeding, hepatic or renal dysfunction

The changes to 2016-17 guidance are:

  • improved layout and readability
  • removal of links to withdrawn and expired documents
  • updated content in section 1.3.4 “Unlicensed treatments”
  • updated appendices including a new summary algorithm for prescribing antivirals in Appendix 2 and the process for requesting zanamivir aqueous solution
  • a new “frequently asked questions” section at the end of the guidance
Published 23 January 2014
Last updated 10 October 2017 + show all updates
  1. Updated PHE guidance document.
  2. Updated with 2016 to 2017 guidance.
  3. Document entitled "Antiviral prescribing when A(H1N1)pdm09 influenza virus is the dominant circulating strain Update letter, January 2016" has been removed as it was specific to last season and therefore the information contained is no longer applicable.
  4. Update letter for antiviral prescribing when A(H1N1)pdm09 influenza virus is the dominant circulating strain.
  5. Updated guidance for the 2015 to 2016 flu season.
  6. This version (5.1) updates version 5.0 (October 2014) with revised guidance on choice of antivirals in severely immunocompromised individuals.
  7. The following have been uploaded; The use of antivirals for the treatment and prophylaxis of influenza: summary of guidance for healthcare professionals; Letter to clinicians regarding the use of antivirals in influenza
  8. Updated guidance.
  9. First published.