Research and analysis

HPR volume 10 issue 11: news (18 March)

Updated 16 December 2016

PHE’s latest quarterly epidemiological commentary on trends in reports of Staphylococcus Aureus (MRSA and MSSA) and Escherichia Coli bacteraemia, and of Clostridium Difficile infections, mandatorily reported by NHS acute Trusts in England up to October-December 2015, has been published on the GOV.UK website [1].

The report includes tabular and graphical information and provides data for the October-December 2015 quarter (updating the previous report published in September 2015). Some key facts are listed below.

1.1 MRSA bacteraemia

There has been a 13.4% decrease (1.7 to 1.5 reports per 100,000 population) in the rate of all reported MRSA bacteraemia between October-December 2012 and the current quarter (October-December 2015). This is part of an overall decreasing trend beginning from April 2007. Furthermore, between October-December 2014 and October-December 2015 decreases in both the counts and rates of total MRSA bacteraemia have been reported (from 215 to 202 reports, and from 1.6 to 1.5 per 100,000 population, respectively). In addition, this has also been observed for Trust-assigned (from 83 to 71, and from 0.9 to 0.8 per 100,000 bed-days) and CCG-assigned (from 103 to 90, and from 0.8 to 0.7 per 100,000 population), while there has been an increase in Third Party assigned cases (from 29 to 41, and from 0.2 to 0.3 per 100,000 population).

1.2 MSSA bacteraemia

The current quarter (October-December 2015) saw the highest rate of total MSSA bacteremia (19.5 reports per 100,000 population) since the reporting of MSSA bacteraemia cases was initiated in January 2011. The count of total MSSA bacteraemia has increased by 3.3% in the current quarter (October-December 2015, n=2,667) when compared to the same quarter in the previous year (October-December 2014, n=2,581). Similarly, in both the counts and rates of Trust-apportioned MSSA bacteraemia reports, there has been a 3.8% increase from 728 to 756 reports and 8.3 to 8.6 per 100,000 bed-days, respectively, over the same time period.

1.3 E Coli bacteraemia

A 7.3% increase (from 64.7 to 69.4 reports per 100,000 population) has been observed in the rate of all reported E. Coli bacteraemias when comparing the current quarter (October-December 2015) with the same quarter of the previous year (October-December 2014). There has been an overall increase of 7.6% in the rate of bacteraemia from 64.5 to 69.4 reports per 100,000 population since July-September 2012.

1.4 C. Difficile infection (CDI)

Between October-December 2014 and the current quarter (October-December 2015), there has been an increase of 4.9% in both counts and rates of all reported CDI cases (from 3,366 to 3,530 reports and from 24.6 to 25.8 reports per 100,000 population), while the Trust-apportioned CDI counts and rates have both remained steady over the same time period (from 1,306 to 1,305 reports, respectively and 14.9 reports per 100,000 bed-days for both quarters).

1.5 Reference

  1. PHE (10 March 2016). Quarterly Epidemiological Commentary: Mandatory MRSA, MSSA and E. coli bacteraemia, and C. difficile infection data (up to October-December 2015).