Research and analysis

Coronavirus (COVID-19) vaccine adverse reactions

A weekly report covering adverse reactions to approved COVID-19 vaccines

Documents

COVID-19 vaccine Pfizer analysis print

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COVID-19 vaccine AstraZeneca analysis print

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COVID-19 vaccine Moderna analysis print

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COVID-19 vaccine brand unspecified analysis print

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Details

The MHRA has played an active role in responding to the coronavirus pandemic. In relation to COVID-19 vaccines, the MHRA has authorised their supply following a rigorous review of their safety, quality and efficacy. The clinical trials of COVID-19 vaccines have shown them to be effective and acceptably safe; however, as part of its statutory functions, the MHRA is responsible for monitoring these vaccines on an ongoing basis to ensure their benefits continue to outweigh any risks.

This is a requirement for all authorised medicines and vaccines in the UK. This monitoring strategy is continuous, proactive and based on a wide range of information sources, with a dedicated team of scientists reviewing information daily to look for safety issues or unexpected rare events.

This weekly report summarises information received via the Yellow Card scheme and will be published regularly to include other safety investigations carried out by the MHRA under the COVID-19 Vaccine Surveillance Strategy.

This report covers the period 9 December 2020 to 15 September 2021.

Published 5 February 2021
Last updated 23 September 2021 + show all updates
  1. Updated figures up to and including 15 September

  2. Updated the report to include data up to and including 8 September 2021.

  3. Updated the ADR report to include data up to 1 September 2021

  4. Updated the weekly ADR report to cover the period from 9 December 2020 to 25 August 2021.

  5. Updated the ADR report with figures up to and including 18 August.

  6. Updated the report to include information up to and including 11 August

  7. Updated with figures to 4 August 2021

  8. Updated with figures for up to 28 July 2021

  9. Updated report with figures up to and including 21 July

  10. Updated weekly report published with figures up to and including 14 July

  11. Updated with figures up to 7 July 2021

  12. Updates for ADR's summary up to 30 June 2021.

  13. Updated to include new data up to 23 June 2021.

  14. Updated to include new data up to 16 June 2021.

  15. New weekly summary of Yellow Card reporting for Coronavirus Vaccines with data until 9 June 2021

  16. Updated to include new data up to 2 June 2021.

  17. Updated to include new data up to 26 May 2021.

  18. Updated to include new data up to 19 May 2021.

  19. Updated to include new data up to 12 May 2021.

  20. Updated to include new data up to 5 May 2021.

  21. Updated to include new data up to 28 April 2021.

  22. Updated to include new data up to 21 April 2021.

  23. We have uploaded the updated weekly summary of Yellow Card reporting on Coronavirus vaccines' ADRs

  24. Updated to include new data up to 5 April 2021.

  25. Updated to include new data up to 28 March 2021.

  26. Updated to include new data up to 21 March.

  27. Updated to include new data up to 14 March.

  28. Published latest ADR (adverse drug reaction) weekly report and iDAPs, covering the period up to 7 March 2021.

  29. Updated pages and PDF attachments to include data from 9 December 2020 to 28 February 2021.

  30. Published updated report with data to 21 February 2021

  31. Published latest ADR (adverse drug reaction) data, covering the period up to 14 February 2021.

  32. Published latest ADR (adverse drug reaction) data, covering the period up to 7 February 2021.

  33. Published latest ADR (adverse drug reaction) data, covering the period up to 31 January 2021.

  34. First published.