The guidelines were developed utilising an evidence review and extensive consultations with clinicians and other stakeholders. This Update fulfils the commitment made in the Second Edition to undertake a biennial review from 2009. The Second Edition Guidelines remain in place, and this Update should be used in conjunction with them.
The Clinical Guidelines support the DH-initiated National Demand Management Programme for Immunoglobulin to provide guidance on appropriate use, to manage demand and to ensure supply for patients for whom immunoglobulin is life-saving.
Arrangements for future immunoglobulin guideline reviews, in the context of the changes in the wider NHS, are currently under discussion. We will give notification of future arrangements in due course.