The Clinical Guidelines for Immunoglobulin Use, implemented in 2008, are to ensure best practice in the use of immunoglobulin across all indications.
The guidelines were developed utilising an evidence review and extensive consultations with clinicians and other stakeholders. This Update fulfils the commitment made in the Second Edition to undertake a biennial review from 2009. The Second Edition Guidelines remain in place, and this Update should be used in conjunction with them.
The Clinical Guidelines support the DH-initiated National Demand Management Programme for Immunoglobulin to provide guidance on appropriate use, to manage demand and to ensure supply for patients for whom immunoglobulin is life-saving.
Arrangements for future immunoglobulin guideline reviews, in the context of the changes in the wider NHS, are currently under discussion. We will give notification of future arrangements in due course.