Research and analysis

Carbapenemase-producing Gram-negative organisms: laboratory surveillance

Quarterly reports on acquired carbapenemase-producing Gram-negative organisms (CPOs) identified in human samples in England.

• From: UK Health Security Agency
• Published: 27 July 2021
• Last updated: 9 July 2026
  Show all updates

  1. 9 July 2026

     Acquired CPO rate for London in 2025 corrected from 122.8 to 22.8 episodes per 100,00 population.

  2. 28 May 2026

     Added HPR 20(5) quarterly report and associated data tables.

  3. 11 December 2025

     Minor updates to data files for Q3 and Q4 of 2022, and for Q1, Q2, Q3 and Q4 of 2023. Map corrections also made for these reports.

  4. 25 September 2025

     Added HPR 19(9) quarterly report (April to June 2025) and data tables file.

  5. 26 June 2025

     Added HPR 19(6) quarterly report and data file for Q1 2025.

  6. 15 May 2025

     Added survey requests.

  7. 31 March 2025

     Added report and data tables for quarter 4, 2024.

  8. 23 December 2024

     Added HPR 18(11) quarterly report and data file.

  9. 26 September 2024

     Added HPR 18(8) quarterly report and associated data tables.

  10. 25 July 2024

      Added HPR 18(6) quarterly report and associated data tables.

  11. 13 May 2024

      Added HPR 18(5) quarterly report and associated data tables.

  12. 17 April 2024

      Data in table 2 (episodes by specimen type) of HPR 18(1) report & data file corrected.

  13. 15 February 2024

      Added HPR 18(1) quarterly report and associated data file.

  14. 19 September 2023

      Added HPPR 17(11) quarterly report and associated data file.

  15. 23 June 2023

      Added latest report and associated data tables.

  16. 29 March 2023

      Added latest report and associated data tables.

  17. 14 February 2023

      Updated the HPR 17(2) report and data tables (covering October 2020 to September 2022). Figure 4a in the report now shows the rate of CPGNB episodes rather than the number; also the related figure 4a-b in the data file.

  18. 22 November 2022

      Added latest report and associated data tables.

  19. 24 August 2022

      Added HPR 16(9) quarterly report.

  20. 18 August 2022

      A corrected version 2 of the HPR 16(5) report (Q1 2022) has been added, 43 samples having been removed from the data set. These mainly related to the Yorkshire and Humber region, with no significant changes to the overall findings.

  21. 25 May 2022

      Added HPR 16(5) quarterly report.

  22. 25 April 2022

      Added version 2 of HPR 16(4).

  23. 22 March 2022

      Added HPR 16(4) quarterly report.

  24. 7 December 2021

      Added HPR 15(20) report.

  25. 17 August 2021

      Added HPR 15(14) report: April to June 2021 update.

  26. 27 July 2021

      First published.

Applies to England

Documents

Carbapenemase-producing Gram-negative organisms in England since October 2020: quarterly update, Q4 2025

Ref: HPR 20(5)

HTML

Carbapenemase-producing Gram-negative organisms in England since October 2020: quarterly update, Q2 2025

Ref: HPR 19(9)

HTML

CPOs in England since October 2020: quarterly update Q2 2025 – data tables (corrected)

Ref: HPR 19(9)

MS Excel Spreadsheet, 150 KB

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Carbapenemase-producing Gram-negative organisms in England since October 2020: quarterly update, Q1 2025

Ref: HPR 19(6)

HTML

CPOs in England since October 2020: quarterly update Q1 2025 – data tables

Ref: HPR 19(6)

MS Excel Spreadsheet, 161 KB

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Carbapenemase-producing Gram-negative organisms in England since October 2020: quarterly update, Q4 2024

Ref: HPR 19(3)

HTML

CPOs in England since October 2020: quarterly update Q4 2024 – data tables

Ref: HPR 19(3)

MS Excel Spreadsheet, 152 KB

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Carbapenemase-producing Gram-negative organisms in England since October 2020: quarterly update, Q3 2024

Ref: HPR 18(11)

HTML

CPOs in England since October 2020: quarterly update Q3 2024 – data tables

Ref: HPR 18(11)

MS Excel Spreadsheet, 107 KB

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Carbapenemase-producing Gram-negative organisms in England since October 2020: quarterly update, Q2 2024

Ref: HPR 18(8)

HTML

CPOs in England since October 2020: quarterly update Q2 2024 – data tables

Ref: HPR 18(8)

MS Excel Spreadsheet, 79.9 KB

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Carbapenemase-producing Gram-negative organisms in England since October 2020: quarterly update, Q1 2024

Ref: HPR 18(6)

HTML

CPOs in England since October 2020: quarterly update Q1 2024 – data tables

Ref: HPR 18(6)

MS Excel Spreadsheet, 89.5 KB

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Carbapenemase-producing Gram-negative organisms in England since October 2020: quarterly update, Q4 2023

Ref: HPR 18(5)

HTML

CPOs in England since October 2020: quarterly update Q4 2023 – data tables

Ref: HPR 18(5)

MS Excel Spreadsheet, 93.5 KB

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to September 2023

Ref: HPR 18(1)

HTML

ACPGN bacteria in England: October 2020 to September 2023: data tables

Ref: HPR 18(1)

MS Excel Spreadsheet, 73.7 KB

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to June 2023

Ref: Ref: HPR 17(11)

HTML

ACPGN bacteria in England: October 2020 to June 2023: data tables

Ref: HPR 17(11)

MS Excel Spreadsheet, 71.7 KB

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to March 2023

Ref: HPR 17(7) v2

PDF, 625 KB, 28 pages

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to March 2023 – data tables

Ref: UKHSA publications gateway number: GOV-14903; HPR 17(7)

MS Excel Spreadsheet, 72.8 KB

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to December 2022

Ref: HPR 17(4) v2

PDF, 607 KB, 30 pages

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to December 2022 – data tables

Ref: UKHSA publications gateway number: GOV-14466; HPR 17(4)

MS Excel Spreadsheet, 69.1 KB

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to September 2022

Ref: HPR 17(2) v3

PDF, 831 KB, 29 pages

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to September 2022 – data tables

Ref: UKHSA publications gateway number: GOV-14218; HPR 17(2)

MS Excel Spreadsheet, 91 KB

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to June 2022

Ref: UKHSA publications gateway number: GOV-13108; HPR 16(9)

PDF, 2.03 MB, 27 pages

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to March 2022

Ref: UKHSA publication gateway number: GOV-12309; HPR 16(5)

PDF, 851 KB, 27 pages

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to December 2021

Ref: UKHSA publication gateway number GOV-11740: HPR 16(4)

PDF, 1.04 MB, 29 pages

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Acquired carbapenemase-producing Gram-negative bacteria in England: October 2020 to September 2021

Ref: UKHSA publications gateway number: GOV-10594; HPR 15(20)

PDF, 730 KB, 16 pages

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Details

Quarterly analyses of data on acquired carbapenemase-producing Gram-negative organisms in England reported to the Second Generation Surveillance System. The analyses summarise:

• trends and geographical distribution of carbapenemase mechanisms
• species
• sample types
• age and sex of cases

Reports in this series for previous quarters were published by Public Health England.