Guidance

ARSAC notes for guidance: good clinical practice in nuclear medicine

Guidance on licencing and best use of radiopharmaceuticals and sealed radioactive sources in diagnosis, treatment or research.

• From: Administration of Radioactive Substances Advisory Committee
• Published: 17 April 2014
• Last updated: 14 July 2026
  Show all updates

  1. 14 July 2026

     Added new version of notes for guidance.

  2. 31 March 2025

     Updated customer portal links and fixed minor typographical errors.

  3. 25 February 2025

     Updated ARSAC notes for guidance.

  4. 31 May 2024

     Updated links to the new applications portal.

  5. 25 March 2024

     Added March 2024 update.

  6. 16 February 2023

     Added February 2023 update.

  7. 26 January 2022

     Updated 'Notes for guidance on the clinical administration of radiopharmaceuticals and use of sealed radioactive sources' (see page 1 for the latest changes).

  8. 16 September 2021

     Edited ‘Section 3: Applying for a practitioner licence’.

  9. 19 February 2021

     Added February update.

  10. 1 September 2020

      Added September 2020 update for Notes for guidance on the clinical administration of radiopharmaceuticals and use of sealed radioactive sources.

  11. 22 April 2020

      Added April 2020 update for Notes for guidance on the clinical administration of radiopharmaceuticals and use of sealed radioactive sources.

  12. 7 February 2020

      Updated 'Notes for guidance on the clinical administration of radiopharmaceuticals and use of sealed radioactive sources'.

  13. 13 February 2019

      Updated notes to clarify the licencing process.

  14. 30 January 2018

      Replaced 'notes for guidance' document and updated detail text.

  15. 22 February 2017

      Uploaded the 2017 edition of guidance.

  16. 15 January 2016

      January 2016 update to guidance.

  17. 17 April 2014

      First published.

Documents

Notes for guidance on the clinical administration of radiopharmaceuticals and use of sealed radioactive sources

Ref: GOV-21373

PDF, 893 KB, 87 pages

Details

This guidance to good clinical practice for nuclear medicine in the UK is the advice of the Administration of Radioactive Substances Advisory Committee (ARSAC).

The July 2026 version contains notable updates from the previous version, which are explained on page 6.