We use some essential cookies to make this website work.
We’d like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services.
We also use cookies set by other sites to help us deliver content from their services.
You have accepted additional cookies. You can change your cookie settings at any time.
You have rejected additional cookies. You can change your cookie settings at any time.
Departments, agencies and public bodies
News stories, speeches, letters and notices
Detailed guidance, regulations and rules
Reports, analysis and official statistics
Consultations and strategy
Data, Freedom of Information releases and corporate reports
Register to vote Register by 18 June to vote in the General Election on 4 July.
Apply for changes to your marketing authorisation, including minor variations type IA and IB, major variations type II and extensions.
Guidance for the pharmaceutical industry on how to apply to vary a veterinary Marketing Authorisation (MA) or Homeopathic Remedy.
How to use an interrupted time series to evaluate your digital health product.
The latest reproduction number (R) and growth rate of coronavirus (COVID-19).
How the MHRA processes variations to Marketing Authorisations (MAs)
How to use a before-and-after study to evaluate your digital health product.
Climate change is happening and is due to human activities; along with warming, many other changes are occurring such as melting polar ice, rising sea levels and more frequent floods, droughts and heatwaves.
Changing an inheritance after death (a 'variation') and how it can affect amounts of Inheritance and Capital Gains tax due
How to get a parallel import licence for your medicine in the UK, including pharmacovigilance requirements and submitting your application.
How to use an ethnographic study to evaluate your digital health product.
Guidance for manufacturers, importers and distributors.
When to use hydrological and hydraulic modelling as part of a flood risk assessment for a planning application, and the expected standards.
Forms to make a variation to a manufacturer's licence.
Data on the real-world efficacy of the COVID-19 vaccines.
Helping public health practitioners conducting evaluations – developing a logic model to represent how your intervention works.
Design, build and operate APIs in a consistent way
How to notify the MHRA of your intention to carry out a clinical investigation for medical devices.
How to change, revoke or transfer your licence, including if the licence holder dies or becomes bankrupt and find out when changes can be enforced.
Don’t include personal or financial information like your National Insurance number or credit card details.
To help us improve GOV.UK, we’d like to know more about your visit today. Please fill in this survey (opens in a new tab).