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Check full blood counts before prescribing dimethyl fumarate and then every 6 to 12 months. Stop treatment immediately if you suspect progressive multifocal leukoencephalopathy.
Marketing authorisations for carisoprodol are to be suspended after a European review concluded that the risks of treatment outweigh the benefits.
New guidance on contraceptive methods and frequency of pregnancy testing to reduce inadvertent exposures during pregnancy in a woman taking a medicine of teratogenic potential.
National influenza and COVID-19 report, monitoring coronavirus (COVID-19) activity, seasonal flu and other seasonal respiratory illnesses.
Statistics on a range of respiratory diseases in adults and children.
Regular updates on seasonal flu levels during the winter season 2019 to 2020.
The profiles provide an overview of end of life care in England at various geographies.
Prescribers and dispensers should use caution if switching patients between different long-acting formulations of methylphenidate (Concerta XL, Medikinet XL, Equasym XL, Ritalin LA, and generics) as different instructions fo…
Cases of serotonin syndrome have been identified in associated with bupropion, especially in overdose or when bupropion is administered with other drugs with a serotonergic effect.
Repeat enhanced cardiovascular monitoring when restarting fingolimod after treatment interruption,
The authorisation holder for dapagliflozin has withdrawn the indication for type 1 diabetes mellitus. The removal of the type 1 diabetes indication is not due to any new safety concerns and the other indications of dapaglifl…
Anti-cancer therapy with carfilzomib has been associated with cases of cardiac arrest, cardiac failure, and myocardial infarction, including in patients without pre-existing cardiac disorders. Monitor patients for signs and …
Reporting to the new site will enable the MHRA to rapidly identify new and emerging side effects and medical device incidents in COVID-19 treatment, including side effects for medicines taken by patients to manage long-term …
This weekly summary highlights changes in the number of people visiting GPs, going to emergency departments and calling NHS 111.
Evidence does not support any increased risk of cancer in patients who use these medicines.
The changes come over a year after the nation began the transition to living with COVID-19.
Amiodarone has been associated with serious and potentially life-threatening side effects, particularly of the lung, liver, and thyroid gland. We remind healthcare professionals that patients should be supervised and reviewe…
A clinically and cost effective care approach for low back pain using a screening tool to match patients to the right treatment.
Summary of investigations into chemical incidents on farms to ensure the health and welfare of livestock, and food safety, is protected.
MHRA performance metrics for clinical trials and established medicines assessment.
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