Research and analysis

Antenatal and newborn screening KPI data: Q3 summary factsheets (1 October to 31 December 2024)

Published 15 May 2025

Applies to England

© Crown copyright 2025

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This publication is available at https://www.gov.uk/government/publications/quarter-3-kpi-report-1-october-to-31-december-2024/antenatal-and-newborn-screening-kpi-data-q3-summary-factsheets-1-october-to-31-december-2024

This report should be read in conjunction with the full KPI data tables published each quarter.

1. Fetal anomaly screening

1.1 KPI FA2: coverage: fetal anomaly ultrasound

National performance of FA2 (see standard FASP-S02) in quarter 2 2024 to 2025 was 97.0%. FA2 is collected 6 months (2 quarters) in arrears.

Quarter 2 performance

Reporting period Numerator Denominator Performance %
Quarter 2 2024 to 2025 130,345 134,415 97.0%
Region Performance %
East of England 99.1%
London 98.3%
Midlands 98.9%
North East and Yorkshire 86.5%
North West 99.1%
South East 99.0%
South West 98.9%
England 97.0%

1.2 KPI FA3

There is no intention to publish FA3 (see standard FASP-S01) by individual maternity service.

1.3 KPI FA4: combined samples

FA4 (see standard FASP-SO6) was introduced in 2020 to 2021. New KPIs are not published in the first year of data collection. This time is used to improve the data quality and completeness, by revising the definition, adding clarity and / or setting thresholds as required.

In quarter 3 2024 to 2025, national performance of FA4 for inadequate combined samples was 3.9%. FA4 is a KPI where a lower performance is better.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 4,410 114,111 3.9%
Region Performance %
East of England 2.1%
London 1.7%
Midlands 3.3%
North East and Yorkshire 7.5%
North West 4.0%
South East 6.1%
South West 2.3%
England 3.9%

1.4 KPI FA4: quadruple samples

FA4 (see standard FASP-S06) was introduced in 2020 to 2021. New KPIs are not published in the first year of data collection. This time is used to improve the data quality and completeness, by revising the definition, adding clarity and / or setting thresholds as required.

In quarter 3 2024 to 2025, national performance of FA4 for inadequate quadruple samples was 7.5%. FA4 is a KPI where a lower performance is better.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 903 12,114 7.5%
Region Performance %
East of England 5.7%
London 3.1%
Midlands 5.8%
North East and Yorkshire 14.5%
North West 4.8%
South East 11.2%
South West 16.2%
England 7.5%

2. Infectious diseases in pregnancy screening

2.1 KPI ID1: HIV coverage

National performance of ID1 (see standard IDPS-S01) in quarter 3 2024 to 2025 was 99.8%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 159,078 159,377 99.8%
Region Performance %
East of England 99.8%
London 99.9%
Midlands 99.8%
North East and Yorkshire 99.8%
North West 99.7%
South East 99.8%
South West 99.7%
England 99.8%

2.2 KPI ID2: diagnosis/intervention: timely assessment of women with hepatitis B

National performance of ID2 (see standard IDPS-S06) in quarter 3 2024 to 2025 was 74.2%. The submission of data for ID2 has changed in 2023 to 2024 from maternity service self-reporting to the Integrated Screening Outcomes Surveillance Service (ISOSS) to improve consistency and accuracy of data returns. This has led to an expected reduction in performance as a result of more accurate data, and does not reflect a change in practice for screening providers.

In April 2023 the acceptable threshold changed from greater than or equal to 70% to greater than or equal to 75%. Due to the way the chart is currently produced, the acceptable threshold is presented as greater than or equal to 75% for all time periods.

ID2 is a small number KPI, therefore the data should be interpreted with caution.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 98 132 74.2%
Region Performance %
East of England 61.5%
London 75.0%
Midlands 78.3%
North East and Yorkshire 55.0%
North West 100.0%
South East 91.7%
South West 50.0%
England 74.2%

2.3 KPI ID3: coverage: hepatitis B

National performance of ID3 (see standard IDPS-S02) in quarter 3 2024 to 2025 was 99.8%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 159,077 159,371 99.8%
Region Performance %
East of England 99.8%
London 99.9%
Midlands 99.8%
North East and Yorkshire 99.8%
North West 99.7%
South East 99.8%
South West 99.7%
England 99.8%

2.4 KPI ID4: coverage: syphilis

National performance of ID4 (see standard IDPS-S03) in quarter 3 2024 to 2025 was 99.8%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 159,066 159,369 99.8%
Region Performance %
East of England 99.8%
London 99.9%
Midlands 99.8%
North East and Yorkshire 99.8%
North West 99.7%
South East 99.8%
South West 99.7%
England 99.8%

3. Sickle cell and thalassaemia screening

3.1 KPI ST1: coverage: antenatal screening

National performance of ST1 (see standard SCT-S01) in quarter 3 2024 to 2025 was 99.8%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 159,072 159,391 99.8%
Region Performance %
East of England 99.8%
London 99.9%
Midlands 99.8%
North East and Yorkshire 99.8%
North West 99.7%
South East 99.8%
South West 99.6%
England 99.8%

3.2 KPI ST2: test: timeliness of antenatal screening

National performance of ST2 (see standard SCT-S02) in quarter 3 2024 to 2025 was 64.2%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 104,463 162,712 64.2%
Region Performance %
East of England 67.3%
London 58.3%
Midlands 56.5%
North East and Yorkshire 74.1%
North West 61.9%
South East 68.2%
South West 70.5%
England 64.2%

3.3 KPI ST3: test: completion of family origin questionnaire (FOQ)

National performance of ST3 (see standard SCT-S03) in quarter 3 2024 to 2025 was 97.8%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 158,519 162,045 97.8%
Region Performance %
East of England 98.4%
London 97.6%
Midlands 96.2%
North East and Yorkshire 98.7%
North West 97.9%
South East 98.3%
South West 98.6%
England 97.8%

3.4 KPI ST4a: referral: timely offer of prenatal diagnosis (PND) to women at risk of having an infant with sickle cell disease or thalassaemia

National performance of ST4a (see standard SCT-S05) in quarter 3 2024 to 2025 was 58.1%. Thresholds have not yet been set for this KPI.

ST4a is a small number KPI, therefore the data should be interpreted with caution.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 323 556 58.1%
Region Performance %
East of England 70.9%
London 57.4%
Midlands 46.8%
North East and Yorkshire 66.7%
North West 34.2%
South East 70.7%
South West 60.0%
England 58.1%

3.5 KPI ST4b: referral: timely offer of prenatal diagnosis (PND) to couples at risk of having an infant with sickle cell disease or thalassaemia

National performance of ST4b (see standard SCT-S05) in quarter 3 2024 to 2025 was 67.8%. Thresholds have not yet been set for this KPI.

ST4b is a small number KPI, therefore the data should be interpreted with caution.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 257 379 67.8%
Region Performance %
East of England 67.4%
London 74.8%
Midlands 61.8%
North East and Yorkshire 78.0%
North West 40.5%
South East 66.7%
South West 81.8%
England 67.8%

4. Newborn blood spot screening

4.1 KPI NB1: coverage of CCG responsibility at birth

National performance of NB1 (see standard NBS-S01a) in quarter 3 2024 to 2025 was 97.5%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 131,685 135,095 97.5%
Region Performance %
East of England 99.6%
London 97.7%
Midlands 97.2%
North East and Yorkshire 97.3%
North West 96.5%
South East 96.8%
South West 97.7%
England 97.5%

4.2 KPI NB2: test: quality of the blood spot sample

National performance of NB2 (see standard NBS-S06) in quarter 3 2024 to 2025 was 2.7%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 3,794 142,243 2.7%
Region Performance %
East of England 2.1%
London 2.8%
Midlands 2.7%
North East and Yorkshire 2.8%
North West 3.3%
South East 2.6%
South West 2.1%
England 2.7%

4.3 KPI NB4: coverage of movers in

National performance of NB4 (see standard NBS-S01b) in quarter 3 2024 to 2025 was 82.0%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 10,877 13,258 82.0%
Region Performance %
East of England 86.2%
London 72.3%
Midlands 79.7%
North East and Yorkshire 88.8%
North West 86.5%
South East 84.9%
South West 81.8%
England 82.0%

5. Newborn hearing screening

5.1 KPI NH1: coverage

National performance of NH1 (see standard NHSP-S01) in quarter 3 2024 to 2025 was 98.8%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 146,137 147,943 98.8%
Region Performance %
East of England 99.0%
London 98.8%
Midlands 99.0%
North East and Yorkshire 99.0%
North West 97.6%
South East 99.0%
South West 99.1%
England 98.8%

5.2 KPI NH2: diagnosis/intervention – time from screening outcome to attendance at an audiological assessment appointment

National performance of NH2 (see standard NHSP-S05) in quarter 3 2024 to 2025 was 90.1%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 2,229 2,475 90.1%
Region Performance %
East of England 91.7%
London 92.3%
Midlands 87.7%
North East and Yorkshire 88.0%
North West 88.9%
South East 93.3%
South West 94.9%
England 90.1%

6. Newborn and infant physical examination screening

6.1 KPI NP1: coverage

National performance of NP1 (see standard NIPE-S01) in quarter 3 2024 to 2025 was 96.4%.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 134,150 139,209 96.4%
Region Performance %
East of England 96.6%
London 96.5%
Midlands 96.3%
North East and Yorkshire 95.9%
North West 95.9%
South East 96.3%
South West 97.5%
England 96.4%

6.2 KPI NP4: diagnosis/intervention – timeliness of hip clinical assessment or discharge

NP4 (see standard NIPE-S04) was introduced in 2024 to 2025.

In quarter 3 2024 to 2025, national performance of NP4 was 78.6%. As this quarter is the first time data is available for this KPI there is no chart.

Quarter 3 performance

Reporting period Numerator Denominator Performance %
Quarter 3 2024 to 2025 9,514 12,103 78.6%
Region Performance %
East of England 81.2%
London 76.6%
Midlands 83.3%
North East and Yorkshire 75.3%
North West 75.3%
South East 78.3%
South West 79.6%
England 78.6%
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