Pneumococcal disease: cases caused by serotypes covered by Prevenar 13 vaccine
Updated 8 July 2025
Applies to England
© Crown copyright 2025
This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. To view this licence, visit nationalarchives.gov.uk/doc/open-government-licence/version/3 or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: psi@nationalarchives.gov.uk.
Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned.
This publication is available at https://www.gov.uk/government/publications/pneumococcal-disease-cases-caused-by-strains-covered-by-prevenar-13-vaccine/pneumococcal-disease-cases-caused-by-strains-covered-by-prevenar-13-vaccine
The number of invasive pneumococcal disease (IPD) cases due to any of the 13 serotypes in Prevenar13™ was the lowest during the 2020 to 2021 epidemiological year due to the COVID-19 pandemic and its associated restrictions.
As of week 20 of 2024 to 2025, for those aged under 2 years, cumulative weekly case numbers were lower than in any year since the 2017 to 2018 epidemiological year (excluding 2019 to 2020 and 2020 to 2021).
Cumulative weekly case numbers amongst those aged 2 to 4 years were lower compared to the three preceding epidemiological years.
Cumulative weekly case numbers for those in the 5 to 64 years and 65 years and above age groups in epidemiological year 2024 to 2025 were higher compared to all epidemiological years since 2017/2018. However, they have not exceeded the case numbers observed in epidemiological years 2006/2007 and 2009/2010.
In PCV13 less than 2 years
Figure 1. Cumulative weekly number of reports of invasive pneumococcal disease due to any of the serotypes in Prevenar13™: children aged less than 2 years in England by epidemiological year July to June (2017/2018 to 2024/2025 to date)
For comparison purposes, 254, 171 and 22 cases were reported in 2006/2007, 2009/2010 and 2013/2014 epidemiological years, respectively.
In PCV13 2 to 4 years
Figure 2. Cumulative weekly number of reports of invasive pneumococcal disease due to any of the serotypes in Prevenar13™: children aged 2 to 4 years in England by epidemiological year July to June (2017/2018 to 2024/2025 to date)
For comparison purposes, 128, 112 and 10 cases were reported in 2006/2007, 2009/2010 and 2013/2014 epidemiological years, respectively.
In PCV13 5 to 64 years
Figure 3. Cumulative weekly number of reports of invasive pneumococcal disease due to any of the serotypes in Prevenar13™: persons aged 5 to 64 years in England by epidemiological year July to June (2017/2018 to 2024/2025 to date)
For comparison purposes 1,248, 1,247 and 403 cases were reported in 2006/2007, 2009/2010 and 2013/2014 epidemiological years, respectively.
In PCV13 over 65 years
Figure 4. Cumulative weekly number of reports of invasive pneumococcal disease due to any of the serotypes in Prevenar13™: persons aged 65 and over England by epidemiological year July to June (2017/2018 to 2024/2025 to date)
For comparison purposes 1,275, 1,017 and 367 cases were reported in 2006/2007, 2009/2010 and 2013/2014 epidemiological years, respectively.
The graphs are based on week of isolation so numbers for the most recent weeks may not be complete. Numbers of reported cases shown in the graphs are not adjusted to account for any change that may have occurred over time and between age groups in the proportion of all IPD cases that are serotyped.
The 7-valent pneumococcal conjugate vaccine (Prevenar 7™) was introduced into the childhood immunisation schedule on 4 September 2006.
The 13-valent pneumococcal conjugate vaccine (Prevenar 13™) was introduced into the childhood immunisation schedule on 1 April 2010.
The vaccine schedule for this vaccine changed for infants born on or after January 2020 (with doses given at 12 weeks and 1 year of age (1+1) instead of 8 weeks, 16 weeks and 1 year of age (2+1)), which corresponds with week 0 above.
Source: Immunisation and Vaccine Preventable Diseases Division, UKHSA (formerly Public Health England).