Research and analysis

NOIDs causative agents: week 7 (week ending 15 February 2026)

Updated 23 February 2026

The list of causative agents that laboratories must notify the UK Health Security Agency (UKHSA) about has been expanded to include additional notifiable organisms. These became reportable under the Health Protection (Notification) (Amendment) Regulations from 6 April 2025.

Publication of the additional causative agents will begin at a later date, once reporting development work has been undertaken to include them.

This report contains statistics of formal notifications of causative agent test results to UKHSA from diagnostic laboratories in England, under Regulation 4 of the Health Protection (Notifications) Regulations 2010.

The number of notifications in this report reflects test results provided from laboratories to UKHSA before UKHSA interprets or applies standardised case definitions to these test results. Individual test results will not always result in a confirmed diagnosis of a disease, therefore the notifications in this report should not be considered counts of cases and should be interpreted with caution.

Epidemiology reports including confirmed case numbers using standardised case definitions are published separately on a per pathogen or pathogen-group basis.

Laboratories in England have a statutory duty to notify UKHSA of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • Carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia spp
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • hepatitis A
  • hepatitis B
  • hepatitis C
  • hepatitis D
  • hepatitis E
  • influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • measles virus
  • mpox virus
  • mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium Knowlesi
  • Plasmodium Malariae
  • Plasmodium Ovale
  • Plasmodium Vivax
  • polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2026/02 2026/03 2026/04 2026/05 2026/06 2026/07
Arboviruses            
West Nile Virus - 2 - - - -
Bacillus            
Bacillus cereus 14 21 19 27 19 16
Bordetella            
Bordetella pertussis 3 5 3 4 4 2
Borrelia            
Borrelia burgdorferi 21 18 25 15 30 19
Borrelia sp 3 3 28 35 39 26
Brucella            
Brucella sp 3 1 - 5 - -
Burkholderia            
Burkholderia pseudomallei 1 - - - - -
Campylobacter            
Campylobacter coli 16 26 28 16 33 25
Campylobacter fetus - - - 1 - -
Campylobacter gracilis - - - - 1 -
Campylobacter jejuni 202 262 220 268 267 227
Campylobacter other named 1 3 2 6 1 1
Campylobacter rectus - - 2 - - 1
Campylobacter sp 761 823 915 931 1,046 1,039
Campylobacter upsaliensis - 4 1 - 1 -
Campylobacter ureolyticus (bacteroides corrodens) 2 1 2 - 1 1
Chikungunya virus            
Chikungunya virus 1 3 1 1 1 3
Clostridium            
Clostridium botulinum - - 1 - - -
Clostridium perfringens 51 51 29 36 38 50
Coronavirus            
Coronavirus 152 167 220 223 231 282
Human coronavirus 229e 4 10 4 8 13 7
Human coronavirus hku1 2 1 3 1 2 5
Human coronavirus nl63 - 2 1 2 1 4
Human coronavirus oc43 11 8 16 26 20 23
SARS-CoV-2 coronavirus (COVID-19) 675 719 673 661 798 855
SARS-CoV-2 coronavirus (COVID-19) indeterminate 27 28 17 29 18 15
SARS-CoV-2 IgG antibody positive 28 22 57 36 22 25
SARS-CoV-2 total antibody negative 8 16 4 - - -
SARS-CoV-2 total antibody positive 44 34 23 6 7 34
Corynebacterium            
Corynebacterium diphtheriae 3 2 4 1 4 5
Corynebacterium ulcerans - - 3 1 2 1
Coxiella            
Coxiella burnetii - - 1 - - -
Cryptosporidium            
Cryptosporidium cuniculus - - - 1 2 -
Cryptosporidium hominis 9 9 6 5 8 3
Cryptosporidium parvum 13 10 16 12 13 6
Cryptosporidium sp 26 21 30 25 22 39
Cryptosporidium ubiquitum 1 - - - 2 -
Entamoeba            
Entamoeba histolytica 1 7 2 1 2 3
Escherichia            
Escherichia coli O 157 6 9 6 8 4 3
Flaviviruses            
Dengue virus 6 3 1 9 12 5
Giardia            
Giardia intestinalis - 1 2 - - -
Giardia sp 113 134 137 118 123 115
Haemophilus            
Haemophilus influenzae 63 64 71 69 75 64
Hepatitis viruses            
Hepatitis A 19 14 11 14 13 16
Hepatitis B 199 248 292 303 281 243
Hepatitis C 231 213 227 248 253 208
Hepatitis D 4 3 11 7 7 3
Hepatitis E 33 38 44 27 41 41
Influenza virus            
Influenza A 5,526 4,203 3,055 1,979 1,567 1,099
Influenza B 50 57 65 57 45 59
Influenza indeterminate 15 30 5 13 - 2
Influenza ungrouped 112 75 39 33 23 15
Legionella            
Legionella pneumophila 8 8 5 8 9 9
Legionella sp 3 5 4 4 5 1
Listeria            
Listeria monocytogenes 2 2 3 - 3 3
Mycobacterium            
Mycobacterium tuberculosis 84 99 77 117 87 75
Neisseria            
Neisseria meningitidis 35 38 31 34 28 36
Orthopoxvirus            
Mpox virus positive 6 12 29 21 25 36
Paramyxoviruses            
Measles virus 10 16 6 16 10 16
Mumps virus 2 6 7 9 8 9
Plasmodium            
Plasmodium falciparum - 2 9 - 5 -
Plasmodium malariae - - 1 - 1 -
Plasmodium ovale - 2 - - 3 -
Plasmodium vivax - - 1 - 2 -
Polyomavirus            
Polyomavirus BK 73 77 84 75 79 66
Polyomavirus JC 10 12 16 6 18 13
Polyomavirus untyped 9 20 16 18 12 18
Rabies virus            
Rabies virus - - - - - 1
Rickettsia            
Rickettsia sp - - - 1 - -
Rickettsia spotted fever - - 1 - - -
Rickettsia tsutsugamushi 1 - - - - -
Rubella virus            
Rubella virus 5 2 1 - 4 3
Salmonella            
Other salmonellas 58 69 59 49 40 24
Salmonella bareilly - - - 5 - -
Salmonella enterica - - 6 - 5 -
Salmonella enteritidis 39 47 40 42 20 9
Salmonella newport - 6 - - - -
Salmonella saint-paul - 5 - - - -
Salmonella sp 19 16 20 50 80 121
Salmonella stanley 5 - - - - -
Salmonella typhi and paratyphi 14 14 8 17 8 10
Salmonella typhimurium 25 33 48 58 47 20
Shigella            
Shigella boydii 1 1 - - 1 2
Shigella dysenteriae - 3 - - 1 -
Shigella flexneri 20 19 20 6 19 11
Shigella sonnei 23 17 21 15 26 18
Shigella sp 43 50 43 63 66 80
Streptococcus            
Streptococcus group A 73 58 74 44 74 63
Streptococcus pneumoniae 197 141 145 139 154 142
Vibrio            
Vibrio cholerae 1 - 1 - 1 1

Carbapenemase-producing Enterobacterales (CPE)

For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to the Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI).

Week notification received 2026/02 2026/03 2026/04 2026/05 2026/06 2026/07
Citrobacter              
Citrobacter spp IMP - 1 - - - -
  KPC - 3 - - 1 -
  NDM - 2 3 3 - -
  OXA48 2 9 5 4 3 -
  Other - - - 2 - -
Enterobacter              
Enterobacter cloacae complex IMP 4 9 - 3 4 1
  KPC 3 1 3 1 2 1
  NDM 11 6 11 7 2 4
  OXA48 6 3 3 7 3 -
  VIM 2 - - - - -
  Other 3 1 2 2 - 1
Enterobacter roggenkampii OXA48 - - 1 - - -
Other enterobacter spp OXA48 - - 1 - - -
Escherichia              
Escherichia coli IMP 1 1 2 1 2 -
  KPC 7 2 1 - - -
  NDM 22 17 18 22 14 5
  OXA48 17 24 28 33 24 7
  VIM - - 1 - - -
  Other 2 2 4 2 3 -
Escherichia hermannii KPC - - - - 1 -
Klebsiella              
Klebsiella aerogenes KPC - - - 1 - -
  NDM - 1 - - - -
  OXA48 - 1 - - - -
Klebsiella oxytoca IMP - - 1 - - -
  KPC - - 2 1 - -
  NDM - 1 - 1 - 1
  OXA48 2 2 - 1 - -
Klebsiella pneumoniae IMP - - 2 - 1 -
  KPC 8 7 5 5 7 2
  NDM 11 15 11 14 11 1
  OXA48 10 16 7 16 7 -
  VIM 1 2 2 - - -
  Other 1 1 2 3 4 1
Klebsiella pneumoniae subsp ozenae KPC 1 - - - - -
  NDM - - 1 - - -
Klebsiella variicola KPC - 1 1 - - -
Other klebsiella spp OXA48 - - - 1 - -
Kluyvera              
Kluyvera spp OXA48 - - - 1 - -
Leclercia              
Leclercia adecarboxylata KPC - 1 - - - -
Morganella              
Morganella morganii KPC - - - 1 - -
  NDM - - - 1 - -
Pluralibacter              
Pluralibacter gergoviae Other - 1 - - - -
Proteus              
Proteus mirabilis KPC - - - - 1 -
  NDM 2 1 - - - -
  OXA48 - - - 1 1 -
  VIM - - - - 1 -
  Other 2 3 1 1 1 -
Providencia              
Providencia stuartii OXA48 1 - - - - -
Raoultella              
Raoultella ornithinolytica OXA48 - - 1 - - -
Other raoultella spp KPC - - - 1 - -
Serratia              
Serratia marcescens/ureilytica NDM - - 1 - - -

Other carbapenemase-producing Gram-negative organisms

For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to.

Week notification received 2026/02 2026/03 2026/04 2026/05 2026/06 2026/07
Acinetobacter              
Acinetobacter baumannii NDM 1 - - - 2 -
  Other 1 - - - - -
Other acinetobacter spp NDM - - - - 1 -
Pseudomonas              
Pseudomonas aeruginosa IMP - 1 - 1 - -
  NDM 2 2 1 2 2 -
  VIM 1 2 1 2 1 1
  Other 4 6 3 4 1 1
Pseudomonas putida group VIM - - 1 - 2 -
  Other - - - - 1 -
Pseudomonas stutzeri group VIM - 1 - - - -
Other pseudomonas spp VIM - - 1 1 - -
Other              
  NDM 1 - - - - -
  OXA48 - 1 - - - -