Research and analysis

NOIDs causative agents: week 6 (week ending 11 February 2026)

Updated 12 February 2026

The list of causative agents that laboratories must notify the UK Health Security Agency (UKHSA) about has been expanded to include additional notifiable organisms. These became reportable under the Health Protection (Notification) (Amendment) Regulations from 6 April 2025.

Publication of the additional causative agents will begin at a later date, once reporting development work has been undertaken to include them.

This report contains statistics of formal notifications of causative agent test results to UKHSA from diagnostic laboratories in England, under Regulation 4 of the Health Protection (Notifications) Regulations 2010.

The number of notifications in this report reflects test results provided from laboratories to UKHSA before UKHSA interprets or applies standardised case definitions to these test results. Individual test results will not always result in a confirmed diagnosis of a disease, therefore the notifications in this report should not be considered counts of cases and should be interpreted with caution.

Epidemiology reports including confirmed case numbers using standardised case definitions are published separately on a per pathogen or pathogen-group basis.

Laboratories in England have a statutory duty to notify UKHSA of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • Carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia spp
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • hepatitis A
  • hepatitis B
  • hepatitis C
  • hepatitis D
  • hepatitis E
  • influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • measles virus
  • mpox virus
  • mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium Knowlesi
  • Plasmodium Malariae
  • Plasmodium Ovale
  • Plasmodium Vivax
  • polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2026/01 2026/02 2026/03 2026/04 2026/05 2026/06
Arboviruses            
West Nile Virus - - 2 - - -
Bacillus            
Bacillus cereus 13 12 19 19 25 17
Bordetella            
Bordetella pertussis 2 3 5 3 4 4
Borrelia            
Borrelia burgdorferi 28 21 18 25 15 30
Borrelia sp 6 3 3 28 35 39
Brucella            
Brucella sp - 3 1 - 5 -
Burkholderia            
Burkholderia pseudomallei - 1 - - - -
Campylobacter            
Campylobacter coli 12 16 26 28 16 30
Campylobacter fetus - - - - 1 -
Campylobacter gracilis - - - - - 1
Campylobacter jejuni 170 197 266 219 268 233
Campylobacter other named 2 1 3 2 6 1
Campylobacter rectus - - - 2 - -
Campylobacter sp 621 731 788 895 903 1,047
Campylobacter upsaliensis 1 - 4 1 - 1
Campylobacter ureolyticus (bacteroides corrodens) - 2 1 2 - 1
Chikungunya virus            
Chikungunya virus 1 1 3 1 1 1
Clostridium            
Clostridium botulinum - - - 1 - -
Clostridium perfringens 34 51 51 28 36 38
Coronavirus            
Coronavirus 114 152 167 220 223 231
Human coronavirus 229e 3 4 10 4 8 13
Human coronavirus hku1 1 2 1 3 1 2
Human coronavirus nl63 2 - 2 1 2 1
Human coronavirus oc43 3 10 8 16 26 19
SARS-CoV-2 antibody void 2 - - - - -
SARS-CoV-2 coronavirus (COVID-19) 652 675 719 673 661 799
SARS-CoV-2 coronavirus (COVID-19) indeterminate 14 27 28 17 29 18
SARS-CoV-2 IgG antibody negative 4 - - - - -
SARS-CoV-2 IgG antibody positive 24 28 22 57 36 22
SARS-CoV-2 total antibody negative 12 8 16 4 - -
SARS-CoV-2 total antibody positive 15 44 34 23 6 7
Corynebacterium            
Corynebacterium diphtheriae 3 3 2 4 1 4
Corynebacterium ulcerans - - - 3 1 2
Coxiella            
Coxiella burnetii - - - 1 - -
Cryptosporidium            
Cryptosporidium cuniculus - - - - 1 -
Cryptosporidium hominis 5 9 9 6 5 4
Cryptosporidium parvum 17 13 10 16 12 10
Cryptosporidium sp 14 23 20 28 25 30
Cryptosporidium ubiquitum - 1 - - - 2
Entamoeba            
Entamoeba histolytica 2 1 7 2 1 2
Escherichia            
Escherichia coli O 157 3 6 9 6 8 3
Flaviviruses            
Dengue virus 1 6 3 1 9 12
Giardia            
Giardia intestinalis - - 1 1 - -
Giardia sp 84 112 128 131 115 122
Haemophilus            
Haemophilus influenzae 62 63 64 71 69 74
Hepatitis viruses            
Hepatitis A 3 19 14 11 14 11
Hepatitis B 224 199 246 286 297 269
Hepatitis C 190 218 205 215 242 242
Hepatitis D 4 4 3 11 7 7
Hepatitis E 26 32 38 43 26 40
Influenza virus            
Influenza A 6,062 5,525 4,203 3,055 1,979 1,567
Influenza B 56 50 57 65 57 45
Influenza indeterminate 38 15 30 5 13 -
Influenza ungrouped 141 112 75 39 33 23
Legionella            
Legionella pneumophila 2 8 8 5 8 9
Legionella sp 5 3 5 4 4 5
Listeria            
Listeria monocytogenes 4 2 2 3 - 3
Mycobacterium            
Mycobacterium tuberculosis 77 84 97 77 112 86
Neisseria            
Neisseria meningitidis 27 35 38 31 34 28
Orthopoxvirus            
Mpox virus positive 4 6 12 29 21 25
Paramyxoviruses            
Measles virus 9 10 16 6 16 10
Mumps virus 3 2 6 7 9 8
Plasmodium            
Plasmodium falciparum 1 - 2 9 - 5
Plasmodium malariae - - - 1 - 1
Plasmodium ovale - - 2 - - 3
Plasmodium vivax - - - 1 - 2
Polyomavirus            
Polyomavirus BK 44 73 77 84 75 79
Polyomavirus JC 8 10 12 16 6 18
Polyomavirus untyped 8 8 20 16 17 12
Rickettsia            
Rickettsia sp - - - - 1 -
Rickettsia spotted fever - - - 1 - -
Rickettsia tsutsugamushi - 1 - - - -
Rubella virus            
Rubella virus 2 5 2 1 - 4
Salmonella            
Other salmonellas 45 56 67 60 30 17
Salmonella enterica - - - 5 - 5
Salmonella enteritidis 33 39 47 40 24 11
Salmonella newport - - 6 - - -
Salmonella saint-paul - - 5 - - -
Salmonella sp 9 16 17 22 104 126
Salmonella stanley - 5 - - - -
Salmonella typhi and paratyphi 9 14 14 8 15 5
Salmonella typhimurium 15 24 32 47 43 40
Shigella            
Shigella boydii 1 1 1 - - 1
Shigella dysenteriae 1 - 3 - - -
Shigella flexneri 18 20 19 20 5 15
Shigella sonnei 17 23 17 21 13 23
Shigella sp 28 43 49 43 65 75
Streptococcus            
Streptococcus group A 64 71 58 75 43 73
Streptococcus pneumoniae 230 197 141 144 139 152
Vibrio            
Vibrio cholerae - 1 - 1 - 1

Carbapenemase-producing Enterobacterales (CPE)

For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to the Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI).

Week notification received 2026/01 2026/02 2026/03 2026/04 2026/05 2026/06
Citrobacter              
Citrobacter spp IMP - - 1 - - -
  KPC - - 3 - - -
  NDM 2 - 2 3 2 -
  OXA48 2 2 8 5 4 2
  Other - - - - 2 -
Enterobacter              
Enterobacter cloacae complex IMP 4 4 9 - 3 2
  KPC 2 3 1 3 1 1
  NDM 3 11 6 11 7 -
  OXA48 4 6 3 3 7 2
  VIM - 2 - - - -
  Other 1 3 1 2 2 -
Enterobacter roggenkampii OXA48 - - - 1 - -
Other enterobacter spp OXA48 - - - 1 - -
Escherichia              
Escherichia coli IMP 1 1 1 2 1 2
  KPC 7 7 2 1 - -
  NDM 16 22 17 18 22 6
  OXA48 24 17 24 27 32 10
  VIM 2 - - 1 - -
  Other 4 2 2 4 2 -
Escherichia hermannii KPC - - - - - 1
Klebsiella              
Klebsiella aerogenes NDM - - 1 - - -
  OXA48 - - 1 - - -
Klebsiella oxytoca IMP - - - 1 - -
  KPC - - - 2 - -
  NDM 1 - 1 - 1 -
  OXA48 - 2 2 - 1 -
Klebsiella pneumoniae IMP - - - 2 - -
  KPC 4 8 7 5 5 3
  NDM 17 11 15 11 14 3
  OXA48 14 10 16 7 16 4
  VIM 1 1 2 2 - -
  Other 1 1 1 2 3 2
Klebsiella pneumoniae subsp ozenae KPC - 1 - - - -
  NDM - - - 1 - -
Klebsiella variicola KPC - - 1 1 - -
  NDM 1 - - - - -
Kluyvera              
Kluyvera spp OXA48 - - - - 1 -
Leclercia              
Leclercia adecarboxylata KPC - - 1 - - -
Morganella              
Morganella morganii KPC - - - - 1 -
  NDM 2 - - - 1 -
Pluralibacter              
Pluralibacter gergoviae Other - - 1 - - -
Proteus              
Proteus mirabilis NDM 1 2 1 - - -
  OXA48 - - - - 1 -
  Other 2 2 3 1 1 -
Providencia              
Providencia stuartii OXA48 - 1 - - - -
Raoultella              
Raoultella ornithinolytica OXA48 - - - 1 - -
Other raoultella spp KPC - - - - 1 -
  OXA48 1 - - - - -
Serratia              
Serratia marcescens/ureilytica NDM - - - 1 - -

Other carbapenemase-producing Gram-negative organisms

For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to.

Week notification received 2026/01 2026/02 2026/03 2026/04 2026/05 2026/06
Acinetobacter              
Acinetobacter baumannii NDM - 1 - - - -
  Other - 1 - - - -
Pseudomonas              
Pseudomonas aeruginosa IMP - - 1 - 1 -
  NDM 1 2 2 1 1 -
  VIM 2 1 2 1 2 -
  Other 2 4 6 3 4 1
Pseudomonas putida group VIM - - - 1 - -
Pseudomonas stutzeri group VIM - - 1 - - -
Other pseudomonas spp VIM - - - 1 1 -
Other              
  NDM 1 1 - - - -
  OXA48 1 - 1 - - -