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Research and analysis

NOIDs causative agents: week 38 (week ending 20 September 2026)

Updated 22 September 2026

The list of causative agents that laboratories must notify the UK Health Security Agency (UKHSA) about has been expanded to include additional notifiable organisms. These became reportable under the Health Protection (Notification) (Amendment) Regulations from 6 April 2025.

Publication of the additional causative agents will begin at a later date, once reporting development work has been undertaken to include them.

This report contains statistics of formal notifications of causative agent test results to UKHSA from diagnostic laboratories in England, under Regulation 4 of the Health Protection (Notifications) Regulations 2010.

The number of notifications in this report reflects test results provided from laboratories to UKHSA before UKHSA interprets or applies standardised case definitions to these test results. Individual test results will not always result in a confirmed diagnosis of a disease, therefore the notifications in this report should not be considered counts of cases and should be interpreted with caution.

Epidemiology reports including confirmed case numbers using standardised case definitions are published separately on a per pathogen or pathogen-group basis.

Laboratories in England have a statutory duty to notify UKHSA of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia spp
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • hepatitis A
  • hepatitis B
  • hepatitis C
  • hepatitis D
  • hepatitis E
  • influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • measles virus
  • mpox virus
  • mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium Knowlesi
  • Plasmodium Malariae
  • Plasmodium Ovale
  • Plasmodium Vivax
  • polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2026/33 2026/34 2026/35 2026/36 2026/37 2026/38
Arboviruses                
West Nile Virus 1 1 - - 1 1    
Bacillus                
Bacillus cereus 72 58 47 40 36 46    
Bordetella                
Bordetella pertussis 5 1 8 5 10 3    
Borrelia                
Borrelia burgdorferi 66 60 47 33 60 59    
Borrelia other named 1 - - - - -    
Borrelia sp 7 12 7 4 8 7    
Brucella                
Brucella melitensis - - 1 - - -    
Brucella sp 1 1 3 - 2 -    
Campylobacter                
Campylobacter coli 60 62 48 40 43 29    
Campylobacter fetus - - - - - 1    
Campylobacter jejuni 369 325 261 272 270 253    
Campylobacter lari - - 1 - - -    
Campylobacter other named 3 1 2 2 1 1    
Campylobacter rectus - - 1 - - -    
Campylobacter sp 1,260 1,267 1,149 934 1,157 1,099    
Campylobacter upsaliensis 1 3 - 1 - -    
Campylobacter ureolyticus (bacteroides corrodens) - 1 2 - - 1    
Chikungunya virus                
Chikungunya virus 1 5 1 2 1 2    
Clostridium                
Clostridium perfringens 35 41 45 37 38 29    
Clostridium tetani 1 - - - - -    
Coronavirus                
Coronavirus 19 18 22 23 23 30    
Human coronavirus nl63 - - 2 - - -    
Human coronavirus oc43 - 1 - 1 - -    
SARS-CoV-2 coronavirus (COVID-19) 296 288 377 504 772 1,148    
SARS-CoV-2 coronavirus (COVID-19) indeterminate 2 1 - 5 162 3    
SARS-CoV-2 IgG antibody negative - - - - 1 -    
SARS-CoV-2 IgG antibody positive 17 21 39 21 20 27    
SARS-CoV-2 total antibody positive 5 11 9 8 6 13    
Corynebacterium                
Corynebacterium diphtheriae 8 7 7 6 2 3    
Corynebacterium ulcerans 1 - 2 3 2 -    
Coxiella                
Coxiella burnetii - - 1 - - 1    
Cryptosporidium                
Cryptosporidium cuniculus 1 - - - - -    
Cryptosporidium hominis 5 6 - 2 - -    
Cryptosporidium meleagridis 1 - - - - -    
Cryptosporidium parvum 29 27 15 5 10 3    
Cryptosporidium sp 33 71 91 107 140 134    
Cryptosporidium ubiquitum - - 1 - - -    
Entamoeba                
Entamoeba histolytica 2 5 2 5 1 1    
Escherichia                
Escherichia coli O 157 30 38 35 24 45 17    
Flaviviruses                
Dengue virus 3 16 8 2 11 7    
Giardia                
Giardia intestinalis 2 6 5 7 3 1    
Giardia sp 133 143 109 119 144 131    
Haemophilus                
Haemophilus influenzae 53 55 55 43 38 53    
Hepatitis viruses                
Hepatitis A 14 15 9 16 24 28    
Hepatitis B 265 294 263 240 266 237    
Hepatitis C 223 245 258 215 212 200    
Hepatitis D 2 3 6 2 5 7    
Hepatitis E 35 38 55 31 33 51    
Influenza virus                
Influenza A 232 304 310 326 499 630    
Influenza B 48 52 39 21 36 54    
Influenza indeterminate - 2 2 3 2 -    
Influenza ungrouped 3 5 12 4 9 26    
Legionella                
Legionella cherrii - - - - 1 -    
Legionella longbeachae - - - 1 - -    
Legionella pneumophila - 4 15 10 16 13    
Legionella sp 4 2 2 2 5 9    
Listeria                
Listeria monocytogenes 3 8 2 4 5 2    
Mycobacterium                
Mycobacterium tuberculosis 98 132 104 103 101 78    
Neisseria                
Neisseria meningitidis 22 12 10 29 20 31    
Orthopoxvirus                
Mpox virus positive 10 16 16 12 24 15    
Paramyxoviruses                
Measles virus 9 11 4 5 11 9    
Mumps virus 6 3 2 2 1 4    
Plasmodium                
Plasmodium falciparum - 1 - - 3 -    
Polyomavirus                
Polyomavirus BK 87 56 69 69 81 69    
Polyomavirus JC 9 7 13 12 15 10    
Polyomavirus untyped 17 11 18 27 10 22    
Rickettsia                
Rickettsia prowazekii - 1 - 1 - -    
Rickettsia sp - - - - 1 -    
Rickettsia spotted fever 2 1 - 1 1 1    
Rickettsia tsutsugamushi - 1 1 1 - 1    
Rubella virus                
Rubella virus 1 1 2 - 1 5    
Salmonella                
Other salmonellas 73 69 86 72 48 37    
Salmonella anatum - - 6 - - -    
Salmonella blockley - - - 5 - -    
Salmonella chester 7 12 10 - - -    
Salmonella coeln - 8 - - - -    
Salmonella enterica 5 7 6 8 6 6    
Salmonella enteritidis 171 174 190 127 54 45    
Salmonella infantis 6 7 7 - - -    
Salmonella java 5 - - - - -    
Salmonella kentucky 5 - - - - -    
Salmonella muenster - 5 5 - - -    
Salmonella newport 7 7 8 5 - -    
Salmonella ohio - 7 - - - -    
Salmonella saint-paul 7 5 - 6 - -    
Salmonella sp 41 52 55 114 297 309    
Salmonella typhi and paratyphi 13 12 12 21 20 29    
Salmonella typhimurium 38 50 42 29 47 26    
Shigella                
Shigella boydii 1 2 2 2 1 1    
Shigella flexneri 16 7 17 13 13 4    
Shigella sonnei 19 10 17 24 23 17    
Shigella sp 42 64 54 57 98 84    
Streptococcus                
Streptococcus group A 61 151 60 38 49 49    
Streptococcus pneumoniae 81 65 71 71 49 53    
Vibrio                
Vibrio cholerae - 1 1 - 3 -    

Carbapenemase-producing Enterobacterales (CPE)

For all carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to the Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Division.

Week notification received 2026/33 2026/34 2026/35 2026/36 2026/37 2026/38
Citrobacter              
Citrobacter spp KPC 1 - 1 2 1 -
  NDM 5 2 1 6 - 1
  OXA48 3 3 5 9 8 3
  VIM - - 1 - - -
  Other - - 1 - - 1
Enterobacter              
Enterobacter cloacae complex IMP 4 1 1 3 5 -
  KPC 3 6 2 1 5 2
  NDM 18 10 13 9 10 4
  OXA48 5 5 2 7 7 1
  VIM - 1 - 2 1 -
  Other 1 1 1 4 5 2
Enterobacter roggenkampii NDM - 1 - - - -
  Other - 1 - - - -
Other enterobacter spp KPC - - 1 2 - -
  NDM - - - - - 1
  VIM 1 - - - - -
  Other 1 - - - 1 1
Escherichia              
Escherichia coli IMP 2 - 1 1 1 2
  KPC 4 6 6 1 4 -
  NDM 31 21 20 19 22 17
  OXA48 30 22 20 35 44 14
  VIM 1 - - - - -
  Other 3 7 8 5 4 3
Escherichia hermannii IMP - - 1 - - -
Ewingella              
Ewingella americana Other 1 - - - - -
Klebsiella              
Klebsiella aerogenes KPC 1 - - - - -
  NDM 1 - - - - -
  VIM - - - - - 1
  Other - - 1 1 - -
Klebsiella oxytoca IMP - - - - - 1
  KPC 1 3 1 1 - 3
  NDM - - 1 3 1 1
  OXA48 1 1 2 2 2 -
  Other - - - 1 1 -
Klebsiella pneumoniae IMP 3 - - - - -
  KPC 6 7 9 7 9 5
  NDM 12 11 9 9 5 5
  OXA48 22 13 12 10 22 3
  Other 2 1 3 7 4 1
Klebsiella variicola IMP - - 1 - - -
  KPC - - - 1 - -
  VIM - - - - 1 -
Other klebsiella spp IMP - - - - - 1
  KPC - - 1 - - -
  OXA48 - - - - - 1
  Other - - - - - 1
Leclercia              
Leclercia adecarboxylata NDM - 1 - - - -
  Other - 1 - - - -
Morganella              
Morganella morganii NDM - - - 1 - -
Proteus              
Proteus mirabilis NDM 2 - 2 5 3 -
  OXA48 - - - - 1 -
  Other 2 - 2 3 2 1
Providencia              
Providencia spp NDM - - - 1 - -
Raoultella              
Raoultella ornithinolytica KPC - 1 - - - -
Raoultella terrigena OXA48 1 - - - - -
Serratia              
Serratia marcescens/ureilytica OXA48 - 1 - - - -
  VIM - 1 - - - -

Other carbapenemase-producing Gram-negative organisms

For all carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to.

Week notification received 2026/33 2026/34 2026/35 2026/36 2026/37 2026/38
Acinetobacter              
Acinetobacter baumannii NDM - 1 1 1 - 1
  Other 1 - 1 - - -
Acinetobacter bereziniae Other - 1 - - - -
Pseudomonas              
Pseudomonas aeruginosa IMP 1 - 1 1 - -
  NDM - - 1 1 1 -
  VIM 2 - 2 2 - -
  Other 1 1 2 4 2 1
Pseudomonas putida group IMP - - - 1 - -
  NDM - - - 1 - -
  VIM 1 - - - - -
  Other - - - 1 - -
Other pseudomonas spp VIM - - - 1 - -
Other              
  KPC - 1 - - - -