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Research and analysis

NOIDs causative agents: week 37 (week ending 13 September 2026)

Updated 16 September 2026

The list of causative agents that laboratories must notify the UK Health Security Agency (UKHSA) about has been expanded to include additional notifiable organisms. These became reportable under the Health Protection (Notification) (Amendment) Regulations from 6 April 2025.

Publication of the additional causative agents will begin at a later date, once reporting development work has been undertaken to include them.

This report contains statistics of formal notifications of causative agent test results to UKHSA from diagnostic laboratories in England, under Regulation 4 of the Health Protection (Notifications) Regulations 2010.

The number of notifications in this report reflects test results provided from laboratories to UKHSA before UKHSA interprets or applies standardised case definitions to these test results. Individual test results will not always result in a confirmed diagnosis of a disease, therefore the notifications in this report should not be considered counts of cases and should be interpreted with caution.

Epidemiology reports including confirmed case numbers using standardised case definitions are published separately on a per pathogen or pathogen-group basis.

Laboratories in England have a statutory duty to notify UKHSA of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia spp
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • hepatitis A
  • hepatitis B
  • hepatitis C
  • hepatitis D
  • hepatitis E
  • influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • measles virus
  • mpox virus
  • mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium Knowlesi
  • Plasmodium Malariae
  • Plasmodium Ovale
  • Plasmodium Vivax
  • polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2026/32 2026/33 2026/34 2026/35 2026/36 2026/37
Arboviruses            
West Nile Virus 1 1 1 - - 1
Bacillus            
Bacillus cereus 61 72 58 47 40 36
Bordetella            
Bordetella pertussis 2 5 1 8 5 10
Borrelia            
Borrelia burgdorferi 92 66 59 47 32 60
Borrelia other named - 1 - - - -
Borrelia sp 20 7 13 7 5 8
Brucella            
Brucella melitensis - - - 1 - -
Brucella sp 1 1 1 3 - 2
Burkholderia            
Burkholderia pseudomallei 1 - - - - -
Campylobacter            
Campylobacter coli 61 60 62 48 40 35
Campylobacter concisus 1 - - - - -
Campylobacter fetus 1 - - - - -
Campylobacter jejuni 295 369 324 261 271 239
Campylobacter lari - - - 1 - -
Campylobacter other named 2 3 1 2 2 1
Campylobacter rectus - - - 1 - -
Campylobacter sp 1,208 1,260 1,268 1,147 934 1,192
Campylobacter upsaliensis 1 1 3 - 1 -
Campylobacter ureolyticus (bacteroides corrodens) 1 - 1 2 - -
Chikungunya virus            
Chikungunya virus - 1 5 1 2 1
Clostridium            
Clostridium perfringens 30 35 41 45 35 37
Clostridium tetani - 1 - - - -
Coronavirus            
Coronavirus 15 19 18 22 23 23
Human coronavirus nl63 - - - 2 - -
Human coronavirus oc43 - - 1 - 1 -
SARS-CoV-2 coronavirus (COVID-19) 239 296 288 378 505 773
SARS-CoV-2 coronavirus (COVID-19) indeterminate 7 2 1 - 5 162
SARS-CoV-2 IgG antibody negative - - - - - 1
SARS-CoV-2 IgG antibody positive 18 17 21 39 21 20
SARS-CoV-2 total antibody positive 9 5 11 9 8 6
Corynebacterium            
Corynebacterium diphtheriae 5 8 7 7 6 2
Corynebacterium ulcerans 1 1 - 2 3 2
Coxiella            
Coxiella burnetii 1 - - 1 - -
Cryptosporidium            
Cryptosporidium cuniculus - 1 - - - -
Cryptosporidium hominis 3 5 6 - 1 -
Cryptosporidium meleagridis - 1 - - - -
Cryptosporidium parvum 9 29 27 15 5 10
Cryptosporidium sp 48 33 71 91 107 141
Cryptosporidium ubiquitum - - - 1 - -
Entamoeba            
Entamoeba histolytica 5 2 5 2 5 2
Escherichia            
Escherichia coli O 157 23 30 38 33 24 31
Flaviviruses            
Dengue virus 7 3 16 8 2 11
Giardia            
Giardia intestinalis 6 3 7 5 7 3
Giardia sp 106 134 143 109 119 144
Haemophilus            
Haemophilus influenzae 48 53 54 55 43 36
Hepatitis viruses            
Hepatitis A 13 14 15 9 16 23
Hepatitis B 308 265 294 262 237 250
Hepatitis C 227 223 245 258 216 195
Hepatitis D 4 2 3 6 2 5
Hepatitis E 34 35 38 55 31 33
Influenza virus            
Influenza A 153 232 304 310 325 499
Influenza B 36 48 52 39 21 36
Influenza indeterminate - - 2 2 3 2
Influenza ungrouped 2 3 5 12 4 9
Legionella            
Legionella cherrii - - - - - 1
Legionella longbeachae 1 - - - 1 -
Legionella pneumophila 7 - 4 14 9 16
Legionella sp 5 4 2 2 2 5
Listeria            
Listeria monocytogenes 3 3 8 2 4 4
Mycobacterium            
Mycobacterium tuberculosis 115 98 130 104 100 96
Neisseria            
Neisseria meningitidis 24 22 12 10 29 20
Orthopoxvirus            
Mpox virus positive 8 10 16 16 12 24
Paramyxoviruses            
Measles virus 7 9 11 4 5 11
Mumps virus 5 6 3 2 2 1
Plasmodium            
Plasmodium falciparum 31 - 1 - - 3
Plasmodium malariae 2 - - - - -
Plasmodium ovale 1 - - - - -
Plasmodium vivax 1 - - - - -
Polyomavirus            
Polyomavirus BK 83 87 56 69 69 81
Polyomavirus JC 11 9 7 13 12 15
Polyomavirus untyped 12 17 11 18 27 10
Rickettsia            
Rickettsia prowazekii - - 1 - 1 -
Rickettsia spotted fever - 2 1 - 1 1
Rickettsia tsutsugamushi - - 1 1 1 -
Rubella virus            
Rubella virus 6 1 1 2 - 2
Salmonella            
Other salmonellas 63 72 67 71 29 26
Salmonella chester 6 6 12 8 - -
Salmonella coeln - - 8 - - -
Salmonella enterica 8 5 7 6 7 -
Salmonella enteritidis 152 171 173 147 47 30
Salmonella infantis - 6 7 5 - -
Salmonella java - 5 - - - -
Salmonella kentucky 5 5 - - - -
Salmonella muenster - - 5 5 - -
Salmonella newport 6 7 7 8 - -
Salmonella ohio - - 7 - - -
Salmonella poona 6 - - - - -
Salmonella saint-paul 5 7 5 - - -
Salmonella sp 29 44 55 130 271 377
Salmonella typhi and paratyphi 12 13 12 11 21 17
Salmonella typhimurium 26 38 50 35 13 19
Shigella            
Shigella boydii - 1 2 2 2 1
Shigella dysenteriae - - - - - -
Shigella flexneri 10 16 7 16 11 9
Shigella sonnei 11 19 10 17 22 17
Shigella sp 38 42 64 55 61 108
Streptococcus            
Streptococcus group A 56 61 150 60 37 49
Streptococcus pneumoniae 53 81 65 71 71 47
Vibrio            
Vibrio cholerae - - 1 1 - 3

Carbapenemase-producing Enterobacterales (CPE)

For all carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to the Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Division.

Week notification received 2026/32 2026/33 2026/34 2026/35 2026/36 2026/37
Citrobacter              
Citrobacter spp KPC 1 1 - 1 2 -
  NDM 2 4 2 1 4 -
  OXA48 1 3 3 5 7 2
  VIM - - - 1 - -
  Other - - - 1 - -
Enterobacter              
Enterobacter cloacae complex IMP 5 3 1 1 3 -
  KPC 7 3 6 2 1 2
  NDM 25 18 10 13 8 3
  OXA48 4 5 5 2 6 3
  VIM - - 1 - 2 -
  Other 1 1 1 1 4 1
Enterobacter roggenkampii NDM - - 1 - - -
  Other - - 1 - - -
Other enterobacter spp KPC 1 - - - - -
  VIM - 1 - - - -
  Other - 1 - - - -
Escherichia              
Escherichia coli IMP 1 2 - 1 1 -
  KPC 2 4 6 5 1 1
  NDM 26 31 20 20 17 6
  OXA48 21 29 22 20 32 10
  VIM - 1 - - - -
  Other 3 3 7 8 5 1
Escherichia hermannii IMP - - - 1 - -
Ewingella              
Ewingella americana Other - 1 - - - -
Klebsiella              
Klebsiella aerogenes KPC - 1 - - - -
  NDM - 1 - - - -
  OXA48 1 - - - - -
  Other - - - 1 1 -
Klebsiella oxytoca KPC 1 1 3 1 1 -
  NDM - - - 1 2 -
  OXA48 1 1 1 2 2 1
  Other - - - - 1 -
Klebsiella pneumoniae IMP 2 3 - - - -
  KPC 11 5 7 9 6 2
  NDM 12 12 11 9 7 -
  OXA48 17 22 13 12 9 3
  VIM 1 - - - - -
  Other 3 2 1 3 6 1
Klebsiella pneumoniae subsp ozenae NDM 1 - - - - -
Klebsiella variicola IMP - - - 1 - -
  KPC - - - - 1 -
  VIM - - - - - 1
Other klebsiella spp NDM 1 - - - - -
  Other 1 - - - - -
Leclercia              
Leclercia adecarboxylata NDM - - 1 - - -
  Other - - 1 - - -
Morganella              
Morganella morganii NDM - - - - 1 -
Proteus              
Proteus mirabilis NDM 3 1 - 2 5 -
  OXA48 - - - - - 1
  Other - 2 - 2 3 -
Providencia              
Providencia spp NDM - - - - 1 -
Raoultella              
Raoultella ornithinolytica KPC - - 1 - - -
Raoultella terrigena OXA48 - 1 - - - -
Serratia              
Serratia marcescens/ureilytica OXA48 - - 1 - - -
  VIM - - 1 - - -

Other carbapenemase-producing Gram-negative organisms

For all carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to.

Week notification received 2026/32 2026/33 2026/34 2026/35 2026/36 2026/37
Acinetobacter              
Acinetobacter baumannii NDM - - 1 1 1 -
  Other - 1 - 1 - -
Acinetobacter bereziniae Other - - 1 - - -
Acinetobacter variabilis NDM 1 - - - - -
Other acinetobacter spp NDM 1 - - - - -
Pseudomonas              
Pseudomonas aeruginosa IMP - 1 - 1 1 -
  NDM 1 - - 1 1 -
  VIM - 2 - 2 1 -
  Other 1 1 1 2 3 -
Pseudomonas putida group IMP - - - - 1 -
  NDM - - - - 1 -
  VIM - 1 - - - -
  Other - - - - 1 -
Other pseudomonas spp VIM - - - - 1 -
Other              
  KPC - - 1 - - -