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Research and analysis

NOIDs causative agents: week 36 (week ending 6 September 2026)

Updated 7 September 2026

The list of causative agents that laboratories must notify the UK Health Security Agency (UKHSA) about has been expanded to include additional notifiable organisms. These became reportable under the Health Protection (Notification) (Amendment) Regulations from 6 April 2025.

Publication of the additional causative agents will begin at a later date, once reporting development work has been undertaken to include them.

This report contains statistics of formal notifications of causative agent test results to UKHSA from diagnostic laboratories in England, under Regulation 4 of the Health Protection (Notifications) Regulations 2010.

The number of notifications in this report reflects test results provided from laboratories to UKHSA before UKHSA interprets or applies standardised case definitions to these test results. Individual test results will not always result in a confirmed diagnosis of a disease, therefore the notifications in this report should not be considered counts of cases and should be interpreted with caution.

Epidemiology reports including confirmed case numbers using standardised case definitions are published separately on a per pathogen or pathogen-group basis.

Laboratories in England have a statutory duty to notify UKHSA of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia spp
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • hepatitis A
  • hepatitis B
  • hepatitis C
  • hepatitis D
  • hepatitis E
  • influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • measles virus
  • mpox virus
  • mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium Knowlesi
  • Plasmodium Malariae
  • Plasmodium Ovale
  • Plasmodium Vivax
  • polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2026/31 2026/32 2026/33 2026/34 2026/35 2026/36
Arboviruses            
West Nile Virus - - 1 1 - -
Bacillus            
Bacillus cereus 68 61 72 58 47 40
Bordetella            
Bordetella pertussis 7 2 5 1 7 5
Borrelia            
Borrelia burgdorferi 96 92 66 57 47 31
Borrelia other named - - 1 - - -
Borrelia sp 5 20 7 15 7 5
Brucella            
Brucella sp 1 1 1 1 4 -
Burkholderia            
Burkholderia pseudomallei 2 1 - - - -
Campylobacter            
Campylobacter coli 67 61 60 62 48 35
Campylobacter concisus - 1 - - - -
Campylobacter fetus - 1 - - - -
Campylobacter jejuni 363 295 368 323 260 225
Campylobacter lari - - - - 1 -
Campylobacter other named 3 2 3 1 2 2
Campylobacter rectus - - - - 1 -
Campylobacter sp 1,236 1,207 1,261 1,268 1,146 979
Campylobacter upsaliensis 2 1 1 3 - 1
Campylobacter ureolyticus (bacteroides corrodens) - 1 - 1 2 -
Chikungunya virus            
Chikungunya virus 2 - 1 5 1 2
Clostridium            
Clostridium perfringens 31 30 35 41 45 34
Clostridium tetani - - 1 - - -
Coronavirus            
Coronavirus 26 15 19 18 22 23
Human coronavirus nl63 - - - - 2 -
Human coronavirus oc43 - - - 1 - 1
SARS-CoV-2 coronavirus (COVID-19) 200 239 296 288 378 505
SARS-CoV-2 coronavirus (COVID-19) indeterminate 7 7 2 1 - 5
SARS-CoV-2 IgG antibody positive 20 18 17 21 39 21
SARS-CoV-2 total antibody positive 8 9 5 11 9 8
Corynebacterium            
Corynebacterium diphtheriae 9 5 8 7 7 6
Corynebacterium ulcerans 1 1 1 - 2 3
Coxiella            
Coxiella burnetii 2 1 - - 1 -
Cryptosporidium            
Cryptosporidium cuniculus - - 1 - - -
Cryptosporidium hominis - 3 5 6 - -
Cryptosporidium meleagridis - - 1 - - -
Cryptosporidium parvum 12 9 28 27 15 5
Cryptosporidium sp 69 48 34 71 91 108
Cryptosporidium ubiquitum - - - - 1 -
Entamoeba            
Entamoeba histolytica 1 5 2 5 2 5
Escherichia            
Escherichia coli O 157 21 23 30 37 31 16
Flaviviruses            
Dengue virus 7 7 3 16 8 2
Giardia            
Giardia intestinalis 1 6 3 6 5 6
Giardia sp 85 106 134 143 109 118
Haemophilus            
Haemophilus influenzae 55 48 53 54 55 43
Hepatitis viruses            
Hepatitis A 7 13 14 15 9 15
Hepatitis B 216 316 270 284 245 210
Hepatitis C 247 227 223 245 250 197
Hepatitis D 5 4 2 3 6 2
Hepatitis E 37 34 35 38 55 29
Influenza virus            
Influenza A 152 153 232 304 310 324
Influenza B 29 36 48 52 39 21
Influenza indeterminate 2 - - 2 2 3
Influenza ungrouped 2 2 3 5 12 4
Legionella            
Legionella longbeachae - 1 - - - 1
Legionella pneumophila 4 7 - 4 14 8
Legionella sp 7 5 4 2 2 3
Listeria            
Listeria monocytogenes 5 3 3 8 2 4
Mycobacterium            
Mycobacterium tuberculosis 126 114 98 126 92 94
Neisseria            
Neisseria meningitidis 16 24 22 12 10 29
Orthopoxvirus            
Mpox virus positive 5 8 10 16 16 12
Paramyxoviruses            
Measles virus 9 7 9 11 4 5
Mumps virus 5 5 6 3 2 2
Plasmodium            
Plasmodium falciparum - 31 - 1 - -
Plasmodium malariae - 2 - - - -
Plasmodium ovale - 1 - - - -
Plasmodium vivax - 1 - - - -
Polyomavirus            
Polyomavirus BK 72 83 87 56 69 69
Polyomavirus JC 8 11 9 7 13 12
Polyomavirus untyped 12 12 17 11 18 27
Rickettsia            
Rickettsia prowazekii 1 - - 1 - 1
Rickettsia spotted fever 1 - 2 1 - 1
Rickettsia tsutsugamushi - - - 1 1 1
Rubella virus            
Rubella virus 1 6 1 1 2 -
Salmonella            
Other salmonellas 78 63 70 53 44 21
Salmonella chester - 6 6 10 - -
Salmonella coeln - - - 7 - -
Salmonella enterica 9 8 5 7 - -
Salmonella enteritidis 138 151 171 146 59 24
Salmonella infantis 5 - 6 6 - -
Salmonella java - - 5 - - -
Salmonella kentucky - 5 5 - - -
Salmonella muenster - - - 5 - -
Salmonella newport 9 6 7 5 - -
Salmonella ohio - - - 7 - -
Salmonella panama 5 - - - - -
Salmonella poona - 6 - - - -
Salmonella saint-paul - 5 7 5 - -
Salmonella sp 48 29 47 107 296 319
Salmonella typhi and paratyphi 9 12 13 12 11 14
Salmonella typhimurium 41 26 38 45 15 10
Shigella            
Shigella boydii - - 1 2 1 2
Shigella flexneri 16 10 15 7 15 7
Shigella sonnei 11 11 19 10 15 19
Shigella sp 41 38 43 64 59 67
Streptococcus            
Streptococcus group A 61 56 61 150 59 35
Streptococcus pneumoniae 81 53 81 65 71 70
Vibrio            
Vibrio cholerae 2 - - 1 1 -

Carbapenemase-producing Enterobacterales (CPE)

For all carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to the Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Division.

Week notification received 2026/31 2026/32 2026/33 2026/34 2026/35 2026/36
Citrobacter              
Citrobacter spp KPC 1 1 1 - 1 2
NDM 1 2 4 2 1 1  
OXA48 3 1 2 3 4 1  
VIM - - - - 1 -  
Other - - - - 1 -  
Enterobacter              
Enterobacter cloacae complex IMP 1 5 3 1 1 -
KPC 6 7 3 6 2 -  
NDM 22 25 18 10 11 -  
OXA48 7 4 5 5 2 1  
VIM - - - 1 - -  
Other 2 1 1 1 1 -  
Enterobacter roggenkampii NDM - - - 1 - -
Other - - - 1 - -  
Other enterobacter spp KPC - 1 - - - -
VIM - - 1 - - -  
Other - - 1 - - -  
Escherichia              
Escherichia coli IMP - 1 2 - 1 -
KPC 2 2 4 6 5 -  
NDM 15 26 31 20 19 6  
OXA48 23 21 29 22 20 8  
VIM 1 - 1 - - -  
Other 1 3 3 7 8 1  
Escherichia hermannii IMP - - - - 1 -
NDM 1 - - - - -  
Ewingella              
Ewingella americana Other - - 1 - - -
Klebsiella              
Klebsiella aerogenes NDM 1 - 1 - - -
OXA48 1 1 - - - -  
Other - - - - 1 -  
Klebsiella oxytoca KPC - 1 1 3 1 -
NDM 1 - - - 1 -  
OXA48 - 1 1 1 1 -  
VIM 1 - - - - -  
Other 1 - - - - 1  
Klebsiella pneumoniae IMP 3 2 3 - - -
KPC 14 10 5 7 8 2  
NDM 12 11 12 11 8 2  
OXA48 19 17 22 13 12 4  
VIM - 1 - - - -  
Other 3 3 2 1 2 1  
Klebsiella pneumoniae subsp ozenae NDM - 1 - - - -
Klebsiella variicola IMP - - - - 1 -
KPC - - - - - 1  
Other klebsiella spp KPC 1 - - - - -
NDM - 1 - - - -  
Other - 1 - - - -  
Leclercia              
Leclercia adecarboxylata NDM - - - 1 - -
Other - - - 1 - -  
Proteus              
Proteus mirabilis NDM 1 3 1 - 2 -
Other - - 2 - 2 -  
Raoultella              
Raoultella ornithinolytica KPC - - - 1 - -
Raoultella terrigena OXA48 - - 1 - - -

Other carbapenemase-producing Gram-negative organisms

For all carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to.

Week notification received 2026/31 2026/32 2026/33 2026/34 2026/35 2026/36
Acinetobacter              
Acinetobacter baumannii NDM - - - - 1 -
Other 1 - 1 - 1 -  
Acinetobacter bereziniae Other - - - 1 - -
Acinetobacter calcoaceticus/baumannii complex NDM 1 - - - - -
Acinetobacter variabilis NDM - 1 - - - -
Other acinetobacter spp NDM - 1 - - - -
Pseudomonas              
Pseudomonas aeruginosa IMP 1 - 1 - 1 -
NDM 1 1 - - 1 -  
VIM - - 2 - 2 -  
Other 2 1 1 1 2 1  
Pseudomonas putida group VIM - - 1 - - -
Other              
  KPC - - - 1 - -