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Research and analysis

NOIDs causative agents: week 32 (week ending 8 August 2026)

Updated 18 August 2026

The list of causative agents that laboratories must notify the UK Health Security Agency (UKHSA) about has been expanded to include additional notifiable organisms. These became reportable under the Health Protection (Notification) (Amendment) Regulations from 6 April 2025.

Publication of the additional causative agents will begin at a later date, once reporting development work has been undertaken to include them.

This report contains statistics of formal notifications of causative agent test results to UKHSA from diagnostic laboratories in England, under Regulation 4 of the Health Protection (Notifications) Regulations 2010.

The number of notifications in this report reflects test results provided from laboratories to UKHSA before UKHSA interprets or applies standardised case definitions to these test results. Individual test results will not always result in a confirmed diagnosis of a disease, therefore the notifications in this report should not be considered counts of cases and should be interpreted with caution.

Epidemiology reports including confirmed case numbers using standardised case definitions are published separately on a per pathogen or pathogen-group basis.

Laboratories in England have a statutory duty to notify UKHSA of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia spp
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • hepatitis A
  • hepatitis B
  • hepatitis C
  • hepatitis D
  • hepatitis E
  • influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • measles virus
  • mpox virus
  • mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium Knowlesi
  • Plasmodium Malariae
  • Plasmodium Ovale
  • Plasmodium Vivax
  • polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2026/27 2026/28 2026/29 2026/30 2026/31 2026/32
Arboviruses            
West Nile Virus - 1 - 1 - -
Bacillus            
Bacillus cereus 61 51 64 71 68 59
Bordetella            
Bordetella pertussis 5 2 4 4 7 3
Borrelia            
Borrelia burgdorferi 68 80 197 79 93 92
Borrelia other named 1 - 2 - - -
Borrelia sp 11 16 12 12 6 21
Brucella            
Brucella canis - - 1 - - -
Brucella sp 5 - 2 - - 1
Burkholderia            
Burkholderia pseudomallei 1 - 1 - 2 1
Campylobacter            
Campylobacter coli 58 56 64 36 67 52
Campylobacter concisus - - - - - 1
Campylobacter fetus 1 - 1 1 - 1
Campylobacter gracilis - 1 1 - - -
Campylobacter jejuni 441 332 321 329 361 244
Campylobacter lari - 1 1 - - -
Campylobacter other named 5 1 3 7 3 2
Campylobacter rectus 1 - - - - -
Campylobacter sp 1,475 1,363 1,193 1,357 1,239 1,256
Campylobacter upsaliensis - - 1 1 1 1
Campylobacter ureolyticus (bacteroides corrodens) - - 3 2 - 1
Chikungunya virus            
Chikungunya virus - 2 - 3 2 -
Clostridium            
Clostridium perfringens 44 34 42 50 31 30
Coronavirus            
Coronavirus 13 21 19 24 26 16
Human coronavirus 229e - 1 1 - - -
Human coronavirus hku1 - 1 1 - - -
Human coronavirus nl63 - 1 1 - - -
SARS-CoV-2 coronavirus (COVID-19) 83 109 111 121 200 238
SARS-CoV-2 coronavirus (COVID-19) indeterminate - 1 - 4 7 7
SARS-CoV-2 IgG antibody negative 1 - 1 - - -
SARS-CoV-2 IgG antibody positive 33 21 22 22 20 18
SARS-CoV-2 total antibody positive 13 1 8 4 8 9
Corynebacterium            
Corynebacterium diphtheriae 4 1 7 5 9 5
Corynebacterium ulcerans 1 - 1 - 1 1
Coxiella            
Coxiella burnetii - - 1 - 2 1
Cryptosporidium            
Cryptosporidium hominis 4 7 2 1 - 1
Cryptosporidium parvum 54 58 19 19 11 5
Cryptosporidium sp 32 55 53 67 70 53
Cryptosporidium ubiquitum 1 1 - - - -
Entamoeba            
Entamoeba histolytica 3 7 5 3 1 5
Escherichia            
Escherichia coli O 157 19 14 23 26 20 17
Flaviviruses            
Dengue virus 11 11 4 4 7 7
Giardia            
Giardia intestinalis 2 5 1 1 1 6
Giardia sp 139 120 118 117 85 105
Haemophilus            
Haemophilus influenzae 84 100 59 62 55 48
Hepatitis viruses            
Hepatitis A 16 13 18 13 7 13
Hepatitis B 287 278 311 298 209 292
Hepatitis C 242 226 228 243 238 207
Hepatitis D 7 12 5 4 5 4
Hepatitis E 39 42 572 43 37 33
Influenza virus            
Influenza A 85 68 95 116 151 151
Influenza B 39 41 44 37 28 36
Influenza indeterminate 6 - - 1 2 -
Influenza ungrouped - 1 3 4 2 2
Legionella            
Legionella longbeachae - - - - - 1
Legionella other named 1 - - - - -
Legionella pneumophila 10 14 7 13 3 7
Legionella sp 4 7 1 5 8 6
Listeria            
Listeria monocytogenes 5 10 5 12 5 3
Mycobacterium            
Mycobacterium tuberculosis 105 123 92 124 113 102
Neisseria            
Neisseria meningitidis 25 15 25 21 16 25
Orthopoxvirus            
Mpox virus positive 7 5 18 8 5 8
Paramyxoviruses            
Measles virus 31 24 6 9 9 7
Mumps virus 8 8 3 7 5 5
Plasmodium            
Plasmodium falciparum 1 4 3 - - 31
Plasmodium malariae 1 - - - - 2
Plasmodium ovale - - - - - 1
Plasmodium vivax - - - - - 1
Polyomavirus            
Polyomavirus BK 74 97 67 78 72 83
Polyomavirus JC 4 12 6 14 8 11
Polyomavirus untyped 12 21 5 28 12 12
Rickettsia            
Rickettsia prowazekii - - - - 1 -
Rickettsia spotted fever 1 2 1 - 1 -
Rubella virus            
Rubella virus 4 4 7 1 1 6
Salmonella            
Other salmonellas 72 80 77 64 51 21
Salmonella agona - - 5 - - -
Salmonella braenderup 8 - - - - -
Salmonella enterica 7 - - 10 9 -
Salmonella enteritidis 110 107 113 157 69 26
Salmonella java - 5 - - - -
Salmonella kentucky - 5 - 6 - -
Salmonella mikawasima - 8 - - - -
Salmonella newport 5 - - 9 7 -
Salmonella oranienburg 6 22 6 - - -
Salmonella sp 40 61 43 83 170 256
Salmonella typhi and paratyphi 12 13 8 - 9 9
Salmonella typhimurium 35 46 59 45 27 9
Shigella            
Shigella boydii 1 - - 2 - -
Shigella dysenteriae 1 - - - - -
Shigella flexneri 14 11 11 14 15 6
Shigella sonnei 10 14 13 18 9 9
Shigella sp 41 43 24 40 44 46
Streptococcus            
Streptococcus group A 72 97 50 62 59 55
Streptococcus pneumoniae 75 81 65 67 79 51
Vibrio            
Vibrio cholerae - 2 - - 2 -

Carbapenemase-producing Enterobacterales (CPE)

For all carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to the Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Division.

Week notification received 2026/27 2026/28 2026/29 2026/30 2026/31 2026/32
Citrobacter              
Citrobacter spp IMP - - 1 - - -
  KPC - 2 - - 1 -
  NDM - 7 6 1 1 -
  OXA48 7 7 6 4 2 -
  Other 2 1 1 1 - -
Enterobacter              
Enterobacter cloacae complex IMP 2 5 4 6 1 -
  KPC 7 7 6 3 6 1
  NDM 26 13 20 15 19 6
  OXA48 9 4 4 3 6 1
  VIM - 1 1 - - -
  Other 3 1 5 4 2 1
Other enterobacter spp IMP 1 - 1 1 - -
  NDM - 1 - - - -
  OXA48 - 1 - - - -
  Other - 1 - - - -
Escherichia              
Escherichia coli IMP 2 3 1 - - -
  KPC 5 2 2 - 2 -
  NDM 18 17 22 21 13 8
  OXA48 39 24 24 21 21 4
  Other 6 6 6 4 1 2
Escherichia hermannii NDM - 1 - - 1 -
Escherichia vulneris KPC - - 1 - - -
Other escherichia spp NDM 1 - - - - -
Klebsiella              
Klebsiella aerogenes NDM - - - - 1 -
  OXA48 - - 3 - 1 -
  Other - - - 2 - -
Klebsiella oxytoca IMP 1 1 - - - -
  KPC 1 - 2 1 - -
  NDM 1 - 1 - 1 -
  OXA48 1 3 1 - - -
  VIM - - - - 1 -
  Other 1 - - - 1 -
Klebsiella pneumoniae IMP 2 1 1 - 2 -
  KPC 11 13 9 7 12 2
  NDM 11 15 13 6 10 1
  OXA48 13 8 15 16 18 1
  VIM - 2 - - - -
  Other 1 2 2 3 3 1
Klebsiella variicola OXA48 - - 1 - - -
Other klebsiella spp KPC 2 - - - - -
  NDM - - - - - 1
  Other - - - - - 1
Pantoea              
Pantoea septica KPC - - 1 - - -
Other pantoea spp NDM - 1 - - - -
Proteus              
Proteus mirabilis NDM - 2 1 1 1 1
  VIM 1 - - - - -
  Other - 1 2 - - -
Raoultella              
Raoultella ornithinolytica OXA48 - - - 1 - -
Other raoultella spp KPC 1 - - - - -
Serratia              
Serratia marcescens/ureilytica NDM 1 - 1 - - -

Other carbapenemase-producing Gram-negative organisms

For all carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to.

Week notification received 2026/27 2026/28 2026/29 2026/30 2026/31 2026/32
Acinetobacter              
Acinetobacter baumannii NDM - - 1 - - -
  Other - - - - 1 -
Acinetobacter calcoaceticus/baumannii complex NDM - - - - 1 -
Other acinetobacter spp NDM - 1 - 2 - -
  Other - - - 1 - -
Pseudomonas              
Pseudomonas aeruginosa IMP 1 1 - - 1 -
  NDM 1 1 - 1 1 -
  VIM - 1 1 1 - -
  Other 2 2 2 3 2 -
Other              
  KPC - 1 - - - -
  NDM - 1 - - - -
  OXA48 1 - 1 - - -
  Other 1 - - - - -