Research and analysis

NOIDs causative agents: week 10 (week ending 8 March 2026)

Updated 18 March 2026

The list of causative agents that laboratories must notify the UK Health Security Agency (UKHSA) about has been expanded to include additional notifiable organisms. These became reportable under the Health Protection (Notification) (Amendment) Regulations from 6 April 2025.

Publication of the additional causative agents will begin at a later date, once reporting development work has been undertaken to include them.

This report contains statistics of formal notifications of causative agent test results to UKHSA from diagnostic laboratories in England, under Regulation 4 of the Health Protection (Notifications) Regulations 2010.

The number of notifications in this report reflects test results provided from laboratories to UKHSA before UKHSA interprets or applies standardised case definitions to these test results. Individual test results will not always result in a confirmed diagnosis of a disease, therefore the notifications in this report should not be considered counts of cases and should be interpreted with caution.

Epidemiology reports including confirmed case numbers using standardised case definitions are published separately on a per pathogen or pathogen-group basis.

Laboratories in England have a statutory duty to notify UKHSA of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • Carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia spp
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • hepatitis A
  • hepatitis B
  • hepatitis C
  • hepatitis D
  • hepatitis E
  • influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • measles virus
  • mpox virus
  • mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium Knowlesi
  • Plasmodium Malariae
  • Plasmodium Ovale
  • Plasmodium Vivax
  • polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2026/06 2026/07 2026/08 2026/09 2026/10
Arboviruses          
West Nile Virus - - 1 - 1
Bacillus          
Bacillus cereus 19 17 22 19 13
Bordetella          
Bordetella pertussis 4 2 2 3 3
Borrelia          
Borrelia burgdorferi 30 20 14 17 22
Borrelia sp 39 25 36 26 38
Brucella          
Brucella sp - - 1 1 1
Campylobacter          
Campylobacter coli 36 30 16 27 31
Campylobacter fetus - 3 - - -
Campylobacter gracilis 1 - - - -
Campylobacter jejuni 269 281 279 264 315
Campylobacter lari - - 1 - -
Campylobacter other named 1 1 1 2 1
Campylobacter rectus - 1 1 3 -
Campylobacter sp 1,046 992 913 916 950
Campylobacter upsaliensis 1 - 1 3 2
Campylobacter ureolyticus (bacteroides corrodens) 1 1 1 1 2
Chikungunya virus          
Chikungunya virus 1 4 2 1 1
Clostridium          
Clostridium perfringens 38 51 43 37 40
Coronavirus          
Coronavirus 231 282 261 263 250
Human coronavirus 229e 13 7 9 3 10
Human coronavirus hku1 2 5 5 2 4
Human coronavirus nl63 1 4 3 3 7
Human coronavirus oc43 20 23 26 7 30
SARS coronavirus - - - - -
SARS-CoV-2 antibody void - - 2 - -
SARS-CoV-2 coronavirus (COVID-19) 801 931 670 662 515
SARS-CoV-2 coronavirus (COVID-19) indeterminate 18 15 13 22 22
SARS-CoV-2 IgG antibody negative - - 3 - 1
SARS-CoV-2 IgG antibody positive 22 25 40 18 21
SARS-CoV-2 total antibody negative - - - 4 -
SARS-CoV-2 total antibody positive 7 34 9 27 7
Corynebacterium          
Corynebacterium diphtheriae 4 5 7 4 7
Corynebacterium ulcerans 2 1 - 1 -
Cryptosporidium          
Cryptosporidium cuniculus 3 1 - 1 -
Cryptosporidium hominis 8 7 9 5 -
Cryptosporidium meleagridis - - 1 - -
Cryptosporidium parvum 15 21 17 24 38
Cryptosporidium sp 19 19 35 36 51
Cryptosporidium ubiquitum 2 - 1 1 1
Entamoeba          
Entamoeba histolytica 3 3 3 3 3
Escherichia          
Escherichia coli O 157 5 4 6 6 5
Flaviviruses          
Dengue virus 12 6 3 2 5
Giardia          
Giardia intestinalis 1 - 1 2 1
Giardia sp 124 117 105 121 131
Haemophilus          
Haemophilus influenzae 75 66 84 95 76
Hepatitis viruses          
Hepatitis A 13 16 15 17 10
Hepatitis B 298 268 263 259 237
Hepatitis C 265 219 192 246 218
Hepatitis D 7 3 8 5 8
Hepatitis E 44 43 33 44 49
Influenza virus          
Influenza A 1,570 1,108 909 728 494
Influenza B 45 84 43 48 41
Influenza indeterminate - 2 5 1 3
Influenza ungrouped 23 15 10 9 7
Legionella          
Legionella pneumophila 9 10 6 8 8
Legionella sp 5 - 6 4 12
Listeria          
Listeria monocytogenes 3 3 5 3 2
Mycobacterium          
Mycobacterium tuberculosis 90 97 85 121 102
Neisseria          
Neisseria meningitidis 28 36 22 33 25
Orthopoxvirus          
Mpox virus positive 25 36 27 35 34
Paramyxoviruses          
Measles virus 10 17 22 31 32
Mumps virus 8 9 6 1 11
Plasmodium          
Plasmodium falciparum 5 - - - -
Plasmodium malariae 1 - - - -
Plasmodium ovale 3 - - - -
Plasmodium vivax 2 - - - -
Polyomavirus          
Polyomavirus BK 82 67 73 65 88
Polyomavirus JC 18 13 5 15 17
Polyomavirus untyped 12 18 7 21 20
Rabies virus          
Rabies virus - 1 - - -
Rubella virus          
Rubella virus 4 3 7 3 4
Salmonella          
Other salmonellas 65 56 57 48 37
Salmonella bareilly 5 - - - -
Salmonella enterica 7 - - - -
Salmonella enteritidis 37 43 27 35 18
Salmonella java - 8 7 - -
Salmonella newport - - - 6 -
Salmonella saint-paul - - 5 - -
Salmonella sp 19 18 24 56 111
Salmonella stanley - 7 - 5 -
Salmonella typhi and paratyphi 8 14 20 18 16
Salmonella typhimurium 59 41 29 27 12
Shigella          
Shigella boydii 1 3 1 3 1
Shigella dysenteriae 1 1 1 - -
Shigella flexneri 21 16 17 16 10
Shigella sonnei 29 26 19 17 18
Shigella sp 61 65 45 68 84
Streptococcus          
Streptococcus group A 76 67 62 76 55
Streptococcus pneumoniae 157 149 130 153 136
Vibrio          
Vibrio cholerae 1 1 - 1 2

Carbapenemase-producing Enterobacterales (CPE)

For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to the Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI).

Week notification received 2026/06 2026/07 2026/08 2026/09 2026/10
Citrobacter            
Citrobacter spp IMP - 1 1 1 -
  KPC 1 1 - 1 1
  NDM - 3 3 2 -
  OXA48 3 1 3 3 -
  VIM - 1 - - -
  Other - 1 1 - -
Enterobacter            
Enterobacter cloacae complex IMP 4 3 2 - 3
  KPC 2 4 3 - -
  NDM 2 8 8 4 4
  OXA48 3 3 6 2 1
  VIM - - 1 - -
  Other 1 2 - 1 2
Other enterobacter spp KPC - - 1 - -
  NDM - - - 1 -
Escherichia            
Escherichia coli IMP 2 4 - - 1
  KPC - 1 1 1 -
  NDM 18 20 18 11 12
  OXA48 26 33 24 24 9
  VIM - 1 - - -
  Other 3 2 3 1 2
Escherichia hermannii KPC 1 - - - -
Escherichia vulneris NDM - - - 1 -
Klebsiella            
Klebsiella aerogenes OXA48 - - - 1 -
Klebsiella oxytoca IMP - 1 - 1 -
  KPC - 3 - - -
  NDM - 1 1 2 -
  OXA48 - 4 - 3 -
  Other - - 1 - -
Klebsiella pneumoniae IMP 1 1 3 - 4
  KPC 7 4 8 4 3
  NDM 11 12 13 8 11
  OXA48 7 7 12 8 10
  VIM - - 2 - 1
  Other 4 1 2 1 1
Other klebsiella spp NDM - - 1 - -
  Other - - 1 - -
Morganella            
Morganella morganii NDM - 1 - - -
  OXA48 - 1 - - -
Pantoea            
Pantoea septica KPC - - - - 1
Proteus            
Proteus mirabilis KPC 1 - - - -
  NDM - 2 3 2 -
  OXA48 1 - - 1 -
  VIM 1 - - - -
  Other 1 - 1 1 -
Proteus vulgaris NDM - - 1 - -
  OXA48 - - 1 - -
Serratia            
Serratia marcescens/ureilytica OXA48 - - 1 1 -

Other carbapenemase-producing Gram-negative organisms

For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.

Note: the numbers presented here do not include specimens that have been referred to.

Week notification received 2026/06 2026/07 2026/08 2026/09 2026/10
Acinetobacter            
Acinetobacter baumannii IMP - 1 - - -
  NDM 3 - - 2 1
  Other - - - - 1
Other acinetobacter spp NDM 1 1 - - -
Pseudomonas            
Pseudomonas aeruginosa IMP - 2 1 1 -
  NDM 2 2 - 1 1
  VIM 1 1 - - -
  Other 2 1 3 1 1
Pseudomonas putida group VIM 2 - - - -
  Other 1 - - - -
Other            
  VIM - - 1 - -
  Other - 1 - - -