Guidance

Latent TB infection (LTBI): testing and treatment

Advice for commissioners and practitioners implementing local LTBI testing and treatment for migrants.

• From: UK Health Security Agency
• Published: 6 July 2015
• Last updated: 15 December 2025
  Show all updates

  1. 15 December 2025

     Removed 'Short introduction' pdf and 'Implementation algorithm' pdf as these are out of date and will be included another updated document.

  2. 15 July 2025

     Rebranded page to UKHSA. No change to content.

  3. 14 May 2019

     Added 'Latent TB infection testing and treatment programme: technical guidance and specification'.

  4. 10 March 2016

     Moving patient leaflet to its own publication.

  5. 19 February 2016

     Added Latent TB Infection (LTBI) testing and treatment national data entry templates.

  6. 24 November 2015

     Added latent TB testing and treatment: information for patients.

  7. 6 July 2015

     First published.

Documents

Latent TB infection testing and treatment programme: technical guidance and specification

Ref: PHE publications gateway number: GW-404

PDF, 1000 KB, 28 pages

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If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email publications@ukhsa.gov.uk. Please tell us what format you need. It will help us if you say what assistive technology you use.

Latent TB testing and treatment for migrants: a practical guide for commissioners and practitioners

Ref: PHE publications gateway number 2015043

PDF, 1.35 MB, 29 pages

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If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email publications@ukhsa.gov.uk. Please tell us what format you need. It will help us if you say what assistive technology you use.

Latent TB Infection (LTBI) testing and treatment national data entry templates: a user guide for general practitioners, clinical commissioning groups and their clinical support centres

Ref: PHE publications gateway number: 2015655

PDF, 2.5 MB, 38 pages

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If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email publications@ukhsa.gov.uk. Please tell us what format you need. It will help us if you say what assistive technology you use.

Details

This content was originally produced by Public Health England (PHE). This content is now owned and managed by the UK Health Security Agency (UKHSA).

The guide brings together relevant information from NICE guidance, research and learning from areas that have set up or piloted latent TB infection (LTBI) testing and treatment programmes. It offers practical advice on how primary care based LTBI testing and treatment could be implemented locally.

It also provides details of LTBI programmes, outlining:

• who should consider implementing one
• who should be tested
• where testing should take place
• how testing should be done
• how testing and treatment is paid for
• what the data return requirements are

The information leaflet can help GPs and healthcare professionals discuss latent TB infections with patients.