Japanese encephalitis: the green book, chapter 20

Japanese encephalitis immunisation information for public health professionals, including updates.


Japanese encephalitis: the green book, chapter 20

This file may not be suitable for users of assistive technology.

Request an accessible format.
If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email Please tell us what format you need. It will help us if you say what assistive technology you use.


Chapter 20 update patches

Japanese encephalitis (JE) is a mosquito-borne viral encephalitis caused by a flavivirus. It is the leading cause of childhood encephalitis in Asia, with 20,000 to 50,000 cases per annum (Halstead et al., 2008; World Health Organization, 1998).

Published 20 March 2013
Last updated 11 June 2018 + show all updates
  1. • Added note, cases of JE are also reported outside of the normal seasonal period of high transmission • A rapid schedule can be used off license in children from 2 months and adults over 65 years of age where there is genuinely insufficient time to complete the standard schedule. • Information added on the timing of booster doses for different age groups.

  2. Updated to include revisions in epidemiology, current date and the type of vaccine available.

  3. This chapter has been rewritten in light of the Green Cross vaccine being no longer recommended for use in the UK and IXIARO now licenced for infants from 2 months of age.

  4. Updated Body text to include a link to National Archives (chapter update patches) and NHS Choices.

  5. First published.